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Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids.
Martino MR, Gutiérrez-Aguilar M, Yiew NKH, Lutkewitte AJ, Singer JM, McCommis KS, Ferguson D, Liss KHH, Yoshino J, Renkemeyer MK, Smith GI, Cho K, Fletcher JA, Klein S, Patti GJ, Burgess SC, Finck BN. Martino MR, et al. Among authors: singer jm. Cell Rep. 2022 Apr 26;39(4):110733. doi: 10.1016/j.celrep.2022.110733. Cell Rep. 2022. PMID: 35476997 Free PMC article.
Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids.
Martino MR, Gutiérrez-Aguilar M, Yiew NKH, Lutkewitte AJ, Singer JM, McCommis KS, Ferguson D, Liss KHH, Yoshino J, Renkemeyer MK, Smith GI, Cho K, Fletcher JA, Klein S, Patti GJ, Burgess SC, Finck BN. Martino MR, et al. Among authors: singer jm. Cell Rep. 2022 Nov 15;41(7):111633. doi: 10.1016/j.celrep.2022.111633. Cell Rep. 2022. PMID: 36384117 Free PMC article. No abstract available.
Bioactive nanoparticles improve calcium handling in failing cardiac myocytes.
Maxwell JT, Somasuntharam I, Gray WD, Shen M, Singer JM, Wang B, Saafir T, Crawford BH, Jiang R, Murthy N, Davis ME, Wagner MB. Maxwell JT, et al. Among authors: singer jm. Nanomedicine (Lond). 2015 Nov;10(22):3343-57. doi: 10.2217/nnm.15.126. Epub 2015 Jul 30. Nanomedicine (Lond). 2015. PMID: 26223412 Free PMC article.
Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and glycerol-mediated gluconeogenesis in mice.
Yiew NKH, Deja S, Ferguson D, Cho K, Jarasvaraparn C, Jacome-Sosa M, Lutkewitte AJ, Mukherjee S, Fu X, Singer JM, Patti GJ, Burgess SC, Finck BN. Yiew NKH, et al. Among authors: singer jm. bioRxiv [Preprint]. 2023 Aug 24:2023.02.17.528992. doi: 10.1101/2023.02.17.528992. bioRxiv. 2023. PMID: 36824879 Free PMC article. Updated. Preprint.
Adipocyte lipin 1 is positively associated with metabolic health in humans and regulates systemic metabolism in mice.
LaPoint A, Singer JM, Ferguson D, Shew TM, Renkemeyer MK, Palacios H, Field R, Shankaran M, Smith GI, Yoshino J, He M, Patti GJ, Hellerstein MK, Klein S, Brestoff JR, Finck BN, Lutkewitte AJ. LaPoint A, et al. Among authors: singer jm. bioRxiv [Preprint]. 2023 Feb 3:2023.02.01.526676. doi: 10.1101/2023.02.01.526676. bioRxiv. 2023. PMID: 36778276 Free PMC article. Preprint.