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Page 1
Bromodomain inhibitors regulate the C9ORF72 locus in ALS.
Zeier Z, Esanov R, Belle KC, Volmar CH, Johnstone AL, Halley P, DeRosa BA, Khoury N, van Blitterswijk M, Rademakers R, Albert J, Brothers SP, Wuu J, Dykxhoorn DM, Benatar M, Wahlestedt C. Zeier Z, et al. Among authors: belle kc. Exp Neurol. 2015 Sep;271:241-50. doi: 10.1016/j.expneurol.2015.06.017. Epub 2015 Jun 20. Exp Neurol. 2015. PMID: 26099177 Free PMC article.
Genetic analysis and multimodal imaging identify novel mtDNA 12148T>C leading to multisystem dysfunction with tissue-specific heteroplasmy.
Belle K, Kreymerman A, Vadgama N, Ji MH, Randhawa S, Caicedo J, Wong M, Muscat SP, Gifford CA, Lee RT, Nasir J, Young JL, Enns G, Karakikes I, Mercola M, Wood EH. Belle K, et al. medRxiv [Preprint]. 2023 Nov 5:2023.11.03.23297854. doi: 10.1101/2023.11.03.23297854. medRxiv. 2023. PMID: 37961166 Free PMC article. Preprint.
A Double Fail-Safe Approach to Prevent Tumorigenesis and Select Pancreatic β Cells from Human Embryonic Stem Cells.
Qadir MMF, Álvarez-Cubela S, Belle K, Sapir T, Messaggio F, Johnson KB, Umland O, Hardin D, Klein D, Pérez-Álvarez I, Sadiq F, Alcázar O, Inverardi LA, Ricordi C, Buchwald P, Fraker CA, Pastori RL, Domínguez-Bendala J. Qadir MMF, et al. Among authors: belle k. Stem Cell Reports. 2019 Mar 5;12(3):611-623. doi: 10.1016/j.stemcr.2019.01.012. Epub 2019 Feb 14. Stem Cell Reports. 2019. PMID: 30773486 Free PMC article.
C9orf72 promoter hypermethylation is reduced while hydroxymethylation is acquired during reprogramming of ALS patient cells.
Esanov R, Belle KC, van Blitterswijk M, Belzil VV, Rademakers R, Dickson DW, Petrucelli L, Boylan KB, Dykxhoorn DM, Wuu J, Benatar M, Wahlestedt C, Zeier Z. Esanov R, et al. Among authors: belle kc. Exp Neurol. 2016 Mar;277:171-177. doi: 10.1016/j.expneurol.2015.12.022. Epub 2015 Dec 31. Exp Neurol. 2016. PMID: 26746986 Free PMC article.