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2023 | 4 |
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Page 1
Newly identified tree shrew cytochrome P450 2B6 (CYP2B6) and pig CYP2B6b are functional drug-metabolising enzymes.
Xenobiotica. 2022 Jul;52(7):687-696. doi: 10.1080/00498254.2022.2141153. Epub 2022 Nov 3.
Xenobiotica. 2022.
PMID: 36286316
Tree shrew cytochrome P450 2E1 is a functional enzyme that metabolises chlorzoxazone and p-nitrophenol.
Ushirozako G, Murayama N, Tsukiyama-Kohara K, Yamazaki H, Uno Y.
Ushirozako G, et al.
Xenobiotica. 2023 Oct-Nov;53(10-11):573-580. doi: 10.1080/00498254.2023.2280996. Epub 2023 Dec 19.
Xenobiotica. 2023.
PMID: 37934191
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Molecular and functional characterization of flavin-containing monooxygenases (FMO1-6) in tree shrews.
Uno Y, Makiguchi M, Ushirozako G, Tsukiyama-Kohara K, Shimizu M, Yamazaki H.
Uno Y, et al. Among authors: ushirozako g.
Comp Biochem Physiol C Toxicol Pharmacol. 2024 Mar;277:109835. doi: 10.1016/j.cbpc.2024.109835. Epub 2024 Jan 11.
Comp Biochem Physiol C Toxicol Pharmacol. 2024.
PMID: 38215804
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Newly Identified Tree Shrew Cytochrome P450 2A13 is Expressed in Liver and Lung and Encodes a Functional Drug-Metabolizing Enzyme Similar to Dog Cytochrome P450 2A13 and Pig Cytochrome P450 2A19.
Ushirozako G, Noda Y, Murayama N, Kawaguchi H, Tsukiyama-Kohara K, Yamazaki H, Uno Y.
Ushirozako G, et al.
Drug Metab Dispos. 2023 May;51(5):610-617. doi: 10.1124/dmd.122.001152. Epub 2023 Jan 20.
Drug Metab Dispos. 2023.
PMID: 36669854
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Cytochrome P450 1A2 and 2C enzymes autoinduced by omeprazole in dog hepatocytes and human HepaRG and HepaSH cells are involved in omeprazole 5-hydroxylation and sulfoxidation.
Uno Y, Uehara S, Ushirozako G, Murayama N, Suemizu H, Yamazaki H.
Uno Y, et al. Among authors: ushirozako g.
Xenobiotica. 2023 Dec;53(6-7):465-473. doi: 10.1080/00498254.2023.2266840. Epub 2023 Nov 3.
Xenobiotica. 2023.
PMID: 37800661
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Chronic Toxoplasma infection affects gene expression of drug-metabolizing enzymes in mouse liver.
Uno Y, Uehara S, Ushirozako G, Masatani T, Yamazaki H.
Uno Y, et al. Among authors: ushirozako g.
Xenobiotica. 2023 Oct-Nov;53(10-11):581-586. doi: 10.1080/00498254.2023.2286597. Epub 2023 Dec 19.
Xenobiotica. 2023.
PMID: 37991059
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Novel Tree Shrew Cytochrome P450 2Ds (CYP2D8a and CYP2D8b) Are Functional Drug-Metabolizing Enzymes that Metabolize Bufuralol and Dextromethorphan.
Ushirozako G, Murayama N, Tsukiyama-Kohara K, Yamazaki H, Uno Y.
Ushirozako G, et al.
Drug Metab Dispos. 2024 Mar 13;52(4):305-311. doi: 10.1124/dmd.123.001603.
Drug Metab Dispos. 2024.
PMID: 38262704
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