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Page 1
Reactivation of the G1 enhancer landscape underlies core circuitry addiction to SWI/SNF.
Cermakova K, Tao L, Dejmek M, Sala M, Montierth MD, Chan YS, Patel I, Chambers C, Loeza Cabrera M, Hoffman D, Parchem RJ, Wang W, Nencka R, Barbieri E, Hodges HC. Cermakova K, et al. Among authors: dejmek m. Nucleic Acids Res. 2024 Jan 11;52(1):4-21. doi: 10.1093/nar/gkad1081. Nucleic Acids Res. 2024. PMID: 37993417 Free PMC article.
Discovery of isonucleotidic CDNs as potent STING agonists with immunomodulatory potential.
Dejmek M, Šála M, Brazdova A, Vanekova L, Smola M, Klíma M, Břehová P, Buděšínský M, Dračínský M, Procházková E, Zavřel M, Šimák O, Páv O, Boura E, Birkuš G, Nencka R. Dejmek M, et al. Structure. 2022 Aug 4;30(8):1146-1156.e11. doi: 10.1016/j.str.2022.05.012. Epub 2022 Jun 10. Structure. 2022. PMID: 35690061 Free article.
Rational Design of Highly Potent SARS-CoV-2 nsp14 Methyltransferase Inhibitors.
Štefek M, Chalupská D, Chalupský K, Zgarbová M, Dvořáková A, Krafčíková P, Li ASM, Šála M, Dejmek M, Otava T, Chaloupecká E, Kozák J, Kozic J, Vedadi M, Weber J, Mertlíková-Kaiserová H, Nencka R. Štefek M, et al. Among authors: dejmek m. ACS Omega. 2023 Jul 21;8(30):27410-27418. doi: 10.1021/acsomega.3c02815. eCollection 2023 Aug 1. ACS Omega. 2023. PMID: 37546609 Free PMC article.
Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists.
Vavřina Z, Perlíková P, Milisavljević N, Chevrier F, Smola M, Smith J, Dejmek M, Havlíček V, Buděšínský M, Liboska R, Vaneková L, Brynda J, Boura E, Řezáčová P, Hocek M, Birkuš G. Vavřina Z, et al. Among authors: dejmek m. J Med Chem. 2022 Oct 27;65(20):14082-14103. doi: 10.1021/acs.jmedchem.2c01305. Epub 2022 Oct 6. J Med Chem. 2022. PMID: 36201304 Free PMC article.
Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3',3'-c-Di(2'F,2'dAMP).
Pimková Polidarová M, Břehová P, Kaiser MM, Smola M, Dračínský M, Smith J, Marek A, Dejmek M, Šála M, Gutten O, Rulíšek L, Novotná B, Brázdová A, Janeba Z, Nencka R, Boura E, Páv O, Birkuš G. Pimková Polidarová M, et al. Among authors: dejmek m. J Med Chem. 2021 Jun 10;64(11):7596-7616. doi: 10.1021/acs.jmedchem.1c00301. Epub 2021 May 21. J Med Chem. 2021. PMID: 34019405
38 results