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Leptin-receptor-expressing mesenchymal stromal cells represent the main source of bone formed by adult bone marrow.
Cell Stem Cell. 2014 Aug 7;15(2):154-68. doi: 10.1016/j.stem.2014.06.008. Epub 2014 Jun 19.
Cell Stem Cell. 2014.
PMID: 24953181
Free PMC article.
Leptin receptor+ cells promote bone marrow innervation and regeneration by synthesizing nerve growth factor.
Gao X, Murphy MM, Peyer JG, Ni Y, Yang M, Zhang Y, Guo J, Kara N, Embree C, Tasdogan A, Ubellacker JM, Crane GM, Fang S, Zhao Z, Shen B, Morrison SJ.
Gao X, et al. Among authors: peyer jg.
Nat Cell Biol. 2023 Dec;25(12):1746-1757. doi: 10.1038/s41556-023-01284-9. Epub 2023 Nov 27.
Nat Cell Biol. 2023.
PMID: 38012403
Free PMC article.
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Regulatory Considerations for Gene Therapy Products in the US, EU, and Japan.
Halioua-Haubold CL, Peyer JG, Smith JA, Arshad Z, Scholz M, Brindley DA, MacLaren RE.
Halioua-Haubold CL, et al. Among authors: peyer jg.
Yale J Biol Med. 2017 Dec 19;90(4):683-693. eCollection 2017 Dec.
Yale J Biol Med. 2017.
PMID: 29259533
Free PMC article.
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Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal.
Acar M, Kocherlakota KS, Murphy MM, Peyer JG, Oguro H, Inra CN, Jaiyeola C, Zhao Z, Luby-Phelps K, Morrison SJ.
Acar M, et al. Among authors: peyer jg.
Nature. 2015 Oct 1;526(7571):126-30. doi: 10.1038/nature15250. Epub 2015 Sep 23.
Nature. 2015.
PMID: 26416744
Free PMC article.
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