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Aryl hydrocarbon receptor is a tumor promoter in MYCN-amplified neuroblastoma cells through suppression of differentiation.
Chaudhry KA, Jacobi JJ, Gillard BM, Karasik E, Martin JC, da Silva Fernandes T, Hurley E, Feltri ML, Attwood KM, Twist CJ, Smiraglia DJ, Long MD, Bianchi-Smiraglia A. Chaudhry KA, et al. Among authors: jacobi jj. iScience. 2023 Oct 21;26(11):108303. doi: 10.1016/j.isci.2023.108303. eCollection 2023 Nov 17. iScience. 2023. PMID: 38026169 Free PMC article.
Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy.
Affronti HC, Rowsam AM, Pellerite AJ, Rosario SR, Long MD, Jacobi JJ, Bianchi-Smiraglia A, Boerlin CS, Gillard BM, Karasik E, Foster BA, Moser M, Wilton JH, Attwood K, Nikiforov MA, Azabdaftari G, Pili R, Phillips JG, Casero RA Jr, Smiraglia DJ. Affronti HC, et al. Among authors: jacobi jj. Nat Commun. 2020 Jan 7;11(1):52. doi: 10.1038/s41467-019-13950-4. Nat Commun. 2020. PMID: 31911608 Free PMC article.