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The phosphorylation of AMPKβ1 is critical for increasing autophagy and maintaining mitochondrial homeostasis in response to fatty acids.
Proc Natl Acad Sci U S A. 2022 Nov 29;119(48):e2119824119. doi: 10.1073/pnas.2119824119. Epub 2022 Nov 21.
Proc Natl Acad Sci U S A. 2022.
PMID: 36409897
Free PMC article.
Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight loss.
Day EA, Ford RJ, Smith BK, Mohammadi-Shemirani P, Morrow MR, Gutgesell RM, Lu R, Raphenya AR, Kabiri M, McArthur AG, McInnes N, Hess S, Paré G, Gerstein HC, Steinberg GR.
Day EA, et al. Among authors: lu r.
Nat Metab. 2019 Dec;1(12):1202-1208. doi: 10.1038/s42255-019-0146-4. Epub 2019 Dec 9.
Nat Metab. 2019.
PMID: 32694673
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Macrophage AMPK β1 activation by PF-06409577 reduces the inflammatory response, cholesterol synthesis, and atherosclerosis in mice.
Day EA, Townsend LK, Rehal S, Batchuluun B, Wang D, Morrow MR, Lu R, Lundenberg L, Lu JH, Desjardins EM, Smith TKT, Raphenya AR, McArthur AG, Fullerton MD, Steinberg GR.
Day EA, et al. Among authors: lu r.
iScience. 2023 Oct 20;26(11):108269. doi: 10.1016/j.isci.2023.108269. eCollection 2023 Nov 17.
iScience. 2023.
PMID: 38026185
Free PMC article.
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Evolution of Taiwan's health care system.
Rachel Lu JF, Chiang TL.
Rachel Lu JF, et al.
Health Econ Policy Law. 2011 Jan;6(1):85-107. doi: 10.1017/S1744133109990351. Epub 2010 Mar 4.
Health Econ Policy Law. 2011.
PMID: 20199715
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The SGLT2 inhibitor canagliflozin suppresses lipid synthesis and interleukin-1 beta in ApoE deficient mice.
Day EA, Ford RJ, Lu JH, Lu R, Lundenberg L, Desjardins EM, Green AE, Lally JSV, Schertzer JD, Steinberg GR.
Day EA, et al. Among authors: lu r.
Biochem J. 2020 Jun 26;477(12):2347-2361. doi: 10.1042/BCJ20200278.
Biochem J. 2020.
PMID: 32510137
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