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Self-delivering, chemically modified CRISPR RNAs for AAV co-delivery and genome editing in vivo.
Nucleic Acids Res. 2024 Jan 25;52(2):977-997. doi: 10.1093/nar/gkad1125.
Nucleic Acids Res. 2024.
PMID: 38033325
Free PMC article.
Unlike RNA-TBA (rTBA), iso-rTBA, the 2'-5'-linked RNA-thrombin-binding aptamer, is a functional equivalent of TBA.
Wagh AA, Kumar VA, Ravindranathan S, Fernandes M.
Wagh AA, et al.
Chem Commun (Camb). 2023 Feb 2;59(11):1461-1464. doi: 10.1039/d2cc05718b.
Chem Commun (Camb). 2023.
PMID: 36651344
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Favorable 2'-substitution in the loop region of a thrombin-binding DNA aptamer.
Awachat R, Wagh AA, Aher M, Fernandes M, Kumar VA.
Awachat R, et al. Among authors: wagh aa.
Bioorg Med Chem Lett. 2018 Jun 1;28(10):1765-1768. doi: 10.1016/j.bmcl.2018.04.027. Epub 2018 Apr 13.
Bioorg Med Chem Lett. 2018.
PMID: 29678465
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