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Year | Number of Results |
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2020 | 1 |
2021 | 1 |
2022 | 2 |
2023 | 1 |
2024 | 2 |
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Page 1
Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype.
Nat Commun. 2023 Nov 30;14(1):7908. doi: 10.1038/s41467-023-43657-6.
Nat Commun. 2023.
PMID: 38036533
Free PMC article.
Tafbromin selectively targets the TAF1 bromodomain.
Patil S, Cremosnik G, Dötsch L, Flegel J, Schulte B, Maier KC, Žumer K, Cramer P, Janning P, Sievers S, Ziegler S, Waldmann H.
Patil S, et al. Among authors: dotsch l.
Angew Chem Int Ed Engl. 2024 May 27:e202404645. doi: 10.1002/anie.202404645. Online ahead of print.
Angew Chem Int Ed Engl. 2024.
PMID: 38801173
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Identification of a Novel Pseudo-Natural Product Type IV IDO1 Inhibitor Chemotype.
Davies C, Dötsch L, Ciulla MG, Hennes E, Yoshida K, Gasper R, Scheel R, Sievers S, Strohmann C, Kumar K, Ziegler S, Waldmann H.
Davies C, et al. Among authors: dotsch l.
Angew Chem Int Ed Engl. 2022 Oct 4;61(40):e202209374. doi: 10.1002/anie.202209374. Epub 2022 Aug 29.
Angew Chem Int Ed Engl. 2022.
PMID: 35959923
Free PMC article.
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Cell-Based Identification of New IDO1 Modulator Chemotypes.
Hennes E, Lampe P, Dötsch L, Bruning N, Pulvermacher LM, Sievers S, Ziegler S, Waldmann H.
Hennes E, et al. Among authors: dotsch l.
Angew Chem Int Ed Engl. 2021 Apr 26;60(18):9869-9874. doi: 10.1002/anie.202016004. Epub 2021 Mar 24.
Angew Chem Int Ed Engl. 2021.
PMID: 33565680
Free PMC article.
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The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation.
Flegel J, Shaaban S, Jia ZJ, Schulte B, Lian Y, Krzyzanowski A, Metz M, Schneidewind T, Wesseler F, Flegel A, Reich A, Brause A, Xue G, Zhang M, Dötsch L, Stender ID, Hoffmann JE, Scheel R, Janning P, Rastinejad F, Schade D, Strohmann C, Antonchick AP, Sievers S, Moura-Alves P, Ziegler S, Waldmann H.
Flegel J, et al. Among authors: dotsch l.
J Med Chem. 2022 Dec 22;65(24):16268-16289. doi: 10.1021/acs.jmedchem.2c00956. Epub 2022 Dec 2.
J Med Chem. 2022.
PMID: 36459434
Free PMC article.
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Discovery of Covalent Inhibitors Targeting the Transcriptional Enhanced Associate Domain Central Pocket.
Karatas H, Akbarzadeh M, Adihou H, Hahne G, Pobbati AV, Yihui Ng E, Guéret SM, Sievers S, Pahl A, Metz M, Zinken S, Dötsch L, Nowak C, Thavam S, Friese A, Kang C, Hong W, Waldmann H.
Karatas H, et al. Among authors: dotsch l.
J Med Chem. 2020 Oct 22;63(20):11972-11989. doi: 10.1021/acs.jmedchem.0c01275. Epub 2020 Oct 1.
J Med Chem. 2020.
PMID: 32907324
Free PMC article.
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Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator.
Dötsch L, Davies C, Hennes E, Schönfeld J, Kumar A, Guita CDCL, Ehrler JHM, Hiesinger K, Thavam S, Janning P, Sievers S, Knapp S, Proschak E, Ziegler S, Waldmann H.
Dötsch L, et al.
J Med Chem. 2024 Mar 28;67(6):4691-4706. doi: 10.1021/acs.jmedchem.3c02245. Epub 2024 Mar 12.
J Med Chem. 2024.
PMID: 38470246
Free PMC article.
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