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A modified mouse model of Friedreich's ataxia with conditional Fxn allele homozygosity delays onset of cardiomyopathy.
Perfitt TL, Huichalaf C, Gooch R, Kuperman A, Ahn Y, Chen X, Ullas S, Hirenallur-Shanthappa D, Zhan Y, Otis D, Whiteley LO, Bulawa C, Martelli A. Perfitt TL, et al. Among authors: kuperman a. Am J Physiol Heart Circ Physiol. 2024 Feb 1;326(2):H357-H369. doi: 10.1152/ajpheart.00496.2023. Epub 2023 Dec 1. Am J Physiol Heart Circ Physiol. 2024. PMID: 38038720
In vivo overexpression of frataxin causes toxicity mediated by iron-sulfur cluster deficiency.
Huichalaf C, Perfitt TL, Kuperman A, Gooch R, Kovi RC, Brenneman KA, Chen X, Hirenallur-Shanthappa D, Ma T, Assaf BT, Pardo I, Franks T, Monarski L, Cheng TW, Le K, Su C, Somanathan S, Whiteley LO, Bulawa C, Pregel MJ, Martelli A. Huichalaf C, et al. Among authors: kuperman a. Mol Ther Methods Clin Dev. 2022 Feb 7;24:367-378. doi: 10.1016/j.omtm.2022.02.002. eCollection 2022 Mar 10. Mol Ther Methods Clin Dev. 2022. PMID: 35252470 Free PMC article.
Neural adaptation leads to cognitive ethanol dependence.
Robinson BG, Khurana S, Kuperman A, Atkinson NS. Robinson BG, et al. Among authors: kuperman a. Curr Biol. 2012 Dec 18;22(24):2338-41. doi: 10.1016/j.cub.2012.10.038. Epub 2012 Nov 29. Curr Biol. 2012. PMID: 23200990 Free PMC article.
Role of calcium and EPAC in norepinephrine-induced ghrelin secretion.
Mani BK, Chuang JC, Kjalarsdottir L, Sakata I, Walker AK, Kuperman A, Osborne-Lawrence S, Repa JJ, Zigman JM. Mani BK, et al. Among authors: kuperman a. Endocrinology. 2014 Jan;155(1):98-107. doi: 10.1210/en.2013-1691. Epub 2013 Dec 20. Endocrinology. 2014. PMID: 24189139 Free PMC article.