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SLC25A51 decouples the mitochondrial NAD+/NADH ratio to control proliferation of AML cells.
Cell Metab. 2024 Apr 2;36(4):808-821.e6. doi: 10.1016/j.cmet.2024.01.013. Epub 2024 Feb 14.
Cell Metab. 2024.
PMID: 38354740
Enhancing anti-AML activity of venetoclax by isoflavone ME-344 through suppression of OXPHOS and/or purine biosynthesis.
Hurrish KH, Su Y, Patel S, Ramage CL, Carter JL, Edwards H, Buck SA, Wiley SE, Hüttemann M, Polin L, Kushner J, Dzinic SH, White K, Bao X, Li J, Yang J, Boerner J, Hou Z, Al-Atrash G, Konoplev SN, Busquets J, Tiziani S, Matherly LH, Taub JW, Konopleva M, Ge Y, Baran N.
Hurrish KH, et al. Among authors: busquets j.
Res Sq [Preprint]. 2023 Apr 28:rs.3.rs-2843025. doi: 10.21203/rs.3.rs-2843025/v1.
Res Sq. 2023.
PMID: 37162954
Free PMC article.
Updated.
Preprint.
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Enhancing anti-AML activity of venetoclax by isoflavone ME-344 through suppression of OXPHOS and/or purine biosynthesis in vitro.
Hurrish KH, Su Y, Patel S, Ramage CL, Zhao J, Temby BR, Carter JL, Edwards H, Buck SA, Wiley SE, Hüttemann M, Polin L, Kushner J, Dzinic SH, White K, Bao X, Li J, Yang J, Boerner J, Hou Z, Al-Atrash G, Konoplev SN, Busquets J, Tiziani S, Matherly LH, Taub JW, Konopleva M, Ge Y, Baran N.
Hurrish KH, et al. Among authors: busquets j.
Biochem Pharmacol. 2024 Feb;220:115981. doi: 10.1016/j.bcp.2023.115981. Epub 2023 Dec 10.
Biochem Pharmacol. 2024.
PMID: 38081370
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The Combined Treatment With the FLT3-Inhibitor AC220 and the Complex I Inhibitor IACS-010759 Synergistically Depletes Wt- and FLT3-Mutated Acute Myeloid Leukemia Cells.
Lu X, Han L, Busquets J, Collins M, Lodi A, Marszalek JR, Konopleva M, Tiziani S.
Lu X, et al. Among authors: busquets j.
Front Oncol. 2021 Aug 20;11:686765. doi: 10.3389/fonc.2021.686765. eCollection 2021.
Front Oncol. 2021.
PMID: 34490088
Free PMC article.
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