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Page 1
Acquisition of suppressive function by conventional T cells limits antitumor immunity upon Treg depletion.
Sci Immunol. 2023 Dec 15;8(90):eabo5558. doi: 10.1126/sciimmunol.abo5558. Epub 2023 Dec 15.
Sci Immunol. 2023.
PMID: 38100544
Free PMC article.
BACH2 restricts NK cell maturation and function, limiting immunity to cancer metastasis.
Imianowski CJ, Whiteside SK, Lozano T, Evans AC, Benson JD, Courreges CJF, Sadiyah F, Lau CM, Zandhuis ND, Grant FM, Schuijs MJ, Vardaka P, Kuo P, Soilleux EJ, Yang J, Sun JC, Kurosaki T, Okkenhaug K, Halim TYF, Roychoudhuri R.
Imianowski CJ, et al. Among authors: grant fm.
J Exp Med. 2022 Dec 5;219(12):e20211476. doi: 10.1084/jem.20211476. Epub 2022 Sep 30.
J Exp Med. 2022.
PMID: 36178457
Free PMC article.
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The transcription factor BACH2 promotes tumor immunosuppression.
Roychoudhuri R, Eil RL, Clever D, Klebanoff CA, Sukumar M, Grant FM, Yu Z, Mehta G, Liu H, Jin P, Ji Y, Palmer DC, Pan JH, Chichura A, Crompton JG, Patel SJ, Stroncek D, Wang E, Marincola FM, Okkenhaug K, Gattinoni L, Restifo NP.
Roychoudhuri R, et al. Among authors: grant fm.
J Clin Invest. 2016 Feb;126(2):599-604. doi: 10.1172/JCI82884. Epub 2016 Jan 5.
J Clin Invest. 2016.
PMID: 26731475
Free PMC article.
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CCR8 marks highly suppressive Treg cells within tumours but is dispensable for their accumulation and suppressive function.
Whiteside SK, Grant FM, Gyori DS, Conti AG, Imianowski CJ, Kuo P, Nasrallah R, Sadiyah F, Lira SA, Tacke F, Eil RL, Burton OT, Dooley J, Liston A, Okkenhaug K, Yang J, Roychoudhuri R.
Whiteside SK, et al. Among authors: grant fm.
Immunology. 2021 Aug;163(4):512-520. doi: 10.1111/imm.13337. Epub 2021 May 9.
Immunology. 2021.
PMID: 33838058
Free PMC article.
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BACH2 drives quiescence and maintenance of resting Treg cells to promote homeostasis and cancer immunosuppression.
Grant FM, Yang J, Nasrallah R, Clarke J, Sadiyah F, Whiteside SK, Imianowski CJ, Kuo P, Vardaka P, Todorov T, Zandhuis N, Patrascan I, Tough DF, Kometani K, Eil R, Kurosaki T, Okkenhaug K, Roychoudhuri R.
Grant FM, et al.
J Exp Med. 2020 Sep 7;217(9):e20190711. doi: 10.1084/jem.20190711.
J Exp Med. 2020.
PMID: 32515782
Free PMC article.
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A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells.
Nasrallah R, Imianowski CJ, Bossini-Castillo L, Grant FM, Dogan M, Placek L, Kozhaya L, Kuo P, Sadiyah F, Whiteside SK, Mumbach MR, Glinos D, Vardaka P, Whyte CE, Lozano T, Fujita T, Fujii H, Liston A, Andrews S, Cozzani A, Yang J, Mitra S, Lugli E, Chang HY, Unutmaz D, Trynka G, Roychoudhuri R.
Nasrallah R, et al. Among authors: grant fm.
Nature. 2020 Jul;583(7816):447-452. doi: 10.1038/s41586-020-2296-7. Epub 2020 May 13.
Nature. 2020.
PMID: 32499651
Free PMC article.
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Compensation between CSF1R+ macrophages and Foxp3+ Treg cells drives resistance to tumor immunotherapy.
Gyori D, Lim EL, Grant FM, Spensberger D, Roychoudhuri R, Shuttleworth SJ, Okkenhaug K, Stephens LR, Hawkins PT.
Gyori D, et al. Among authors: grant fm.
JCI Insight. 2018 Jun 7;3(11):e120631. doi: 10.1172/jci.insight.120631. eCollection 2018 Jun 7.
JCI Insight. 2018.
PMID: 29875321
Free PMC article.
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