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HKDC1, a target of TFEB, is essential to maintain both mitochondrial and lysosomal homeostasis, preventing cellular senescence.
Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2306454120. doi: 10.1073/pnas.2306454120. Epub 2024 Jan 3.
Proc Natl Acad Sci U S A. 2024.
PMID: 38170752
The TMEM192-mKeima probe specifically assays lysophagy and reveals its initial steps.
Shima T, Ogura M, Matsuda R, Nakamura S, Jin N, Yoshimori T, Kuma A.
Shima T, et al. Among authors: ogura m.
J Cell Biol. 2023 Dec 4;222(12):e202204048. doi: 10.1083/jcb.202204048. Epub 2023 Oct 6.
J Cell Biol. 2023.
PMID: 37801070
Free PMC article.
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Microautophagy regulated by STK38 and GABARAPs is essential to repair lysosomes and prevent aging.
Ogura M, Kaminishi T, Shima T, Torigata M, Bekku N, Tabata K, Minami S, Nishino K, Nezu A, Hamasaki M, Kosako H, Yoshimori T, Nakamura S.
Ogura M, et al.
EMBO Rep. 2023 Dec 6;24(12):e57300. doi: 10.15252/embr.202357300. Epub 2023 Nov 21.
EMBO Rep. 2023.
PMID: 37987447
Free PMC article.
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Protocols to monitor TFEB activation following lysosomal damage in cultured cells using microscopy and immunoblotting.
Ogura M, Shima T, Yoshimori T, Nakamura S.
Ogura M, et al.
STAR Protoc. 2022 Jan 7;3(1):101018. doi: 10.1016/j.xpro.2021.101018. eCollection 2022 Mar 18.
STAR Protoc. 2022.
PMID: 35243365
Free PMC article.
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Neutrophil-Mediated Lung Injury Both via TLR2-Dependent Production of IL-1α and IL-12 p40, and TLR2-Independent CARDS Toxin after Mycoplasma pneumoniae Infection in Mice.
Tamiya S, Yoshikawa E, Ogura M, Kuroda E, Suzuki K, Yoshioka Y.
Tamiya S, et al. Among authors: ogura m.
Microbiol Spectr. 2021 Dec 22;9(3):e0158821. doi: 10.1128/spectrum.01588-21. Epub 2021 Dec 22.
Microbiol Spectr. 2021.
PMID: 34937175
Free PMC article.
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Vaccination using inactivated Mycoplasma pneumoniae induces detrimental infiltration of neutrophils after subsequent infection in mice.
Tamiya S, Yoshikawa E, Ogura M, Kuroda E, Suzuki K, Yoshioka Y.
Tamiya S, et al. Among authors: ogura m.
Vaccine. 2020 Jul 6;38(32):4979-4987. doi: 10.1016/j.vaccine.2020.05.074. Epub 2020 Jun 11.
Vaccine. 2020.
PMID: 32536549
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