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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 12
2003 5
2004 4
2005 5
2006 6
2007 2
2008 5
2010 2
2011 7
2012 5
2013 3
2014 2
2015 4
2016 9
2017 8
2018 9
2019 9
2020 3
2021 4
2022 5
2023 8
2024 5

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113 results

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Page 1
Epigenetic balance ensures mechanistic control of MLL amplification and rearrangement.
Gray ZH, Chakraborty D, Duttweiler RR, Alekbaeva GD, Murphy SE, Chetal K, Ji F, Ferman BI, Honer MA, Wang Z, Myers C, Sun R, Kaniskan HÜ, Toma MM, Bondarenko EA, Santoro JN, Miranda C, Dillingham ME, Tang R, Gozani O, Jin J, Skorski T, Duy C, Lee H, Sadreyev RI, Whetstine JR. Gray ZH, et al. Among authors: skorski t. Cell. 2023 Oct 12;186(21):4528-4545.e18. doi: 10.1016/j.cell.2023.09.009. Epub 2023 Oct 2. Cell. 2023. PMID: 37788669
DNA polymerase θ protects leukemia cells from metabolically induced DNA damage.
Vekariya U, Toma M, Nieborowska-Skorska M, Le BV, Caron MC, Kukuyan AM, Sullivan-Reed K, Podszywalow-Bartnicka P, Chitrala KN, Atkins J, Drzewiecka M, Feng W, Chan J, Chatla S, Golovine K, Jelinek J, Sliwinski T, Ghosh J, Matlawska-Wasowska K, Chandramouly G, Nejati R, Wasik M, Sykes SM, Piwocka K, Hadzijusufovic E, Valent P, Pomerantz RT, Morton G, Childers W, Zhao H, Paietta EM, Levine RL, Tallman MS, Fernandez HF, Litzow MR, Gupta GP, Masson JY, Skorski T. Vekariya U, et al. Among authors: skorski t. Blood. 2023 May 11;141(19):2372-2389. doi: 10.1182/blood.2022018428. Blood. 2023. PMID: 36580665 Free PMC article.
Synthetic Lethality Targeting Polθ.
Drzewiecka M, Barszczewska-Pietraszek G, Czarny P, Skorski T, Śliwiński T. Drzewiecka M, et al. Among authors: skorski t. Genes (Basel). 2022 Jun 20;13(6):1101. doi: 10.3390/genes13061101. Genes (Basel). 2022. PMID: 35741863 Free PMC article. Review.
R-Loop Accumulation in Spliceosome Mutant Leukemias Confers Sensitivity to PARP1 Inhibition by Triggering Transcription-Replication Conflicts.
Liu ZS, Sinha S, Bannister M, Song A, Arriaga-Gomez E, McKeeken AJ, Bonner EA, Hanson BK, Sarchi M, Takashima K, Zong D, Corral VM, Nguyen E, Yoo J, Chiraphapphaiboon W, Leibson C, McMahon MC, Rai S, Swisher EM, Sachs Z, Chatla S, Stirewalt DL, Deeg HJ, Skorski T, Papapetrou EP, Walter MJ, Graubert TA, Doulatov S, Lee SC, Nguyen HD. Liu ZS, et al. Among authors: skorski t. Cancer Res. 2024 Feb 15;84(4):577-597. doi: 10.1158/0008-5472.CAN-23-3239. Cancer Res. 2024. PMID: 37967363
[Uracil-DNA glycosylases].
Pytel D, Słupianek A, Ksiazek D, Skórski T, Błasiak J. Pytel D, et al. Among authors: skorski t. Postepy Biochem. 2008;54(4):362-70. Postepy Biochem. 2008. PMID: 19248582 Review. Polish.
Polθ Inhibition: An Anticancer Therapy for HR-Deficient Tumours.
Barszczewska-Pietraszek G, Drzewiecka M, Czarny P, Skorski T, Śliwiński T. Barszczewska-Pietraszek G, et al. Among authors: skorski t. Int J Mol Sci. 2022 Dec 24;24(1):319. doi: 10.3390/ijms24010319. Int J Mol Sci. 2022. PMID: 36613762 Free PMC article. Review.
TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors.
Maifrede S, Le BV, Nieborowska-Skorska M, Golovine K, Sullivan-Reed K, Dunuwille WMB, Nacson J, Hulse M, Keith K, Madzo J, Caruso LB, Gazze Z, Lian Z, Padella A, Chitrala KN, Bartholdy BA, Matlawska-Wasowska K, Di Marcantonio D, Simonetti G, Greiner G, Sykes SM, Valent P, Paietta EM, Tallman MS, Fernandez HF, Litzow MR, Minden MD, Huang J, Martinelli G, Vassiliou GS, Tempera I, Piwocka K, Johnson N, Challen GA, Skorski T. Maifrede S, et al. Among authors: skorski t. Cancer Res. 2021 Oct 1;81(19):5089-5101. doi: 10.1158/0008-5472.CAN-20-3761. Epub 2021 Jul 2. Cancer Res. 2021. PMID: 34215619 Free PMC article.
Clonal medicine targeting DNA damage response eradicates leukemia.
Toma MM, Karami A, Nieborowska-Skorska M, Chirtala KN, Pepek M, Hadzijusufovic E, Stoklosa T, Valent P, Skorski T. Toma MM, et al. Among authors: skorski t. Leukemia. 2024 Mar;38(3):671-675. doi: 10.1038/s41375-024-02138-5. Epub 2024 Jan 16. Leukemia. 2024. PMID: 38228681 Free PMC article. No abstract available.
Simultaneous Targeting of DNA Polymerase Theta and PARP1 or RAD52 Triggers Dual Synthetic Lethality in Homologous Recombination-Deficient Leukemia Cells.
Sullivan-Reed K, Toma MM, Drzewiecka M, Nieborowska-Skorska M, Nejati R, Karami A, Wasik MA, Sliwinski T, Skorski T. Sullivan-Reed K, et al. Among authors: skorski t. Mol Cancer Res. 2023 Oct 2;21(10):1017-1022. doi: 10.1158/1541-7786.MCR-22-1035. Mol Cancer Res. 2023. PMID: 37358557 Free PMC article.
113 results