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Tracking the mechanism of covalent molecular glue stabilization using native mass spectrometry.
Chem Sci. 2023 May 31;14(24):6756-6762. doi: 10.1039/d3sc01732j. eCollection 2023 Jun 21.
Chem Sci. 2023.
PMID: 37350830
Free PMC article.
Characterizing the protein-protein interaction between MDM2 and 14-3-3σ; proof of concept for small molecule stabilization.
Ward JA, Romartinez-Alonso B, Kay DF, Bellamy-Carter J, Thurairajah B, Basran J, Kwon H, Leney AC, Macip S, Roversi P, Muskett FW, Doveston RG.
Ward JA, et al. Among authors: kay df.
J Biol Chem. 2024 Feb;300(2):105651. doi: 10.1016/j.jbc.2024.105651. Epub 2024 Jan 16.
J Biol Chem. 2024.
PMID: 38237679
Free PMC article.
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