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2011 2
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2015 3
2016 1
2024 1

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Page 1
Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth.
Kleffel S, Posch C, Barthel SR, Mueller H, Schlapbach C, Guenova E, Elco CP, Lee N, Juneja VR, Zhan Q, Lian CG, Thomi R, Hoetzenecker W, Cozzio A, Dummer R, Mihm MC Jr, Flaherty KT, Frank MH, Murphy GF, Sharpe AH, Kupper TS, Schatton T. Kleffel S, et al. Cell. 2015 Sep 10;162(6):1242-56. doi: 10.1016/j.cell.2015.08.052. Cell. 2015. PMID: 26359984 Free PMC article.
Tumor cell-intrinsic PD-1 promotes Merkel cell carcinoma growth by activating downstream mTOR-mitochondrial ROS signaling.
Martins C, Rasbach E, Heppt MV, Singh P, Kulcsar Z, Holzgruber J, Chakraborty A, Mucciarone K, Kleffel S, Brandenburg A, Hoetzenecker W, Rahbari NN, DeCaprio JA, Thakuria M, Murphy GF, Ramsey MR, Posch C, Barthel SR, Schatton T. Martins C, et al. Among authors: kleffel s. Sci Adv. 2024 Jan 19;10(3):eadi2012. doi: 10.1126/sciadv.adi2012. Epub 2024 Jan 19. Sci Adv. 2024. PMID: 38241371 Free PMC article.
ABCB5 Identifies Immunoregulatory Dermal Cells.
Schatton T, Yang J, Kleffel S, Uehara M, Barthel SR, Schlapbach C, Zhan Q, Dudeney S, Mueller H, Lee N, de Vries JC, Meier B, Vander Beken S, Kluth MA, Ganss C, Sharpe AH, Waaga-Gasser AM, Sayegh MH, Abdi R, Scharffetter-Kochanek K, Murphy GF, Kupper TS, Frank NY, Frank MH. Schatton T, et al. Among authors: kleffel s. Cell Rep. 2015 Sep 8;12(10):1564-74. doi: 10.1016/j.celrep.2015.08.010. Epub 2015 Aug 28. Cell Rep. 2015. PMID: 26321644 Free PMC article.
ABCB5-Targeted Chemoresistance Reversal Inhibits Merkel Cell Carcinoma Growth.
Kleffel S, Lee N, Lezcano C, Wilson BJ, Sobolewski K, Saab KR, Mueller H, Zhan Q, Posch C, Elco CP, DoRosario A, Garcia SS, Thakuria M, Wang YE, Wang LC, Murphy GF, Frank MH, Schatton T. Kleffel S, et al. J Invest Dermatol. 2016 Apr;136(4):838-846. doi: 10.1016/j.jid.2015.12.038. Epub 2016 Jan 29. J Invest Dermatol. 2016. PMID: 26827764 Free PMC article.
Nestin depletion induces melanoma matrix metalloproteinases and invasion.
Lee CW, Zhan Q, Lezcano C, Frank MH, Huang J, Larson AR, Lin JY, Wan MT, Lin PI, Ma J, Kleffel S, Schatton T, Lian CG, Murphy GF. Lee CW, et al. Among authors: kleffel s. Lab Invest. 2014 Dec;94(12):1382-95. doi: 10.1038/labinvest.2014.130. Epub 2014 Nov 3. Lab Invest. 2014. PMID: 25365206 Free PMC article.
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma.
Lian CG, Xu Y, Ceol C, Wu F, Larson A, Dresser K, Xu W, Tan L, Hu Y, Zhan Q, Lee CW, Hu D, Lian BQ, Kleffel S, Yang Y, Neiswender J, Khorasani AJ, Fang R, Lezcano C, Duncan LM, Scolyer RA, Thompson JF, Kakavand H, Houvras Y, Zon LI, Mihm MC Jr, Kaiser UB, Schatton T, Woda BA, Murphy GF, Shi YG. Lian CG, et al. Among authors: kleffel s. Cell. 2012 Sep 14;150(6):1135-46. doi: 10.1016/j.cell.2012.07.033. Cell. 2012. PMID: 22980977 Free PMC article.
IL-21 is an antitolerogenic cytokine of the late-phase alloimmune response.
Petrelli A, Carvello M, Vergani A, Lee KM, Tezza S, Du M, Kleffel S, Chengwen L, Mfarrej BG, Hwu P, Secchi A, Leonard WJ, Young D, Sayegh MH, Markmann JF, Zajac AJ, Fiorina P. Petrelli A, et al. Among authors: kleffel s. Diabetes. 2011 Dec;60(12):3223-34. doi: 10.2337/db11-0880. Epub 2011 Oct 19. Diabetes. 2011. PMID: 22013017 Free PMC article.
Long-term heart transplant survival by targeting the ionotropic purinergic receptor P2X7.
Vergani A, Tezza S, D'Addio F, Fotino C, Liu K, Niewczas M, Bassi R, Molano RD, Kleffel S, Petrelli A, Soleti A, Ammirati E, Frigerio M, Visner G, Grassi F, Ferrero ME, Corradi D, Abdi R, Ricordi C, Sayegh MH, Pileggi A, Fiorina P. Vergani A, et al. Among authors: kleffel s. Circulation. 2013 Jan 29;127(4):463-75. doi: 10.1161/CIRCULATIONAHA.112.123653. Epub 2012 Dec 18. Circulation. 2013. PMID: 23250993 Free PMC article.
12 results