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Page 1
Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotype.
Maus M, López-Polo V, Mateo L, Lafarga M, Aguilera M, De Lama E, Meyer K, Sola A, Lopez-Martinez C, López-Alonso I, Guasch-Piqueras M, Hernandez-Gonzalez F, Chaib S, Rovira M, Sanchez M, Faner R, Agusti A, Diéguez-Hurtado R, Ortega S, Manonelles A, Engelhardt S, Monteiro F, Stephan-Otto Attolini C, Prats N, Albaiceta G, Cruzado JM, Serrano M. Maus M, et al. Among authors: chaib s. Nat Metab. 2023 Dec;5(12):2111-2130. doi: 10.1038/s42255-023-00928-2. Epub 2023 Dec 14. Nat Metab. 2023. PMID: 38097808 Free PMC article.
The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2.
Chaib S, López-Domínguez JA, Lalinde-Gutiérrez M, Prats N, Marin I, Boix O, García-Garijo A, Meyer K, Muñoz MI, Aguilera M, Mateo L, Stephan-Otto Attolini C, Llanos S, Pérez-Ramos S, Escorihuela M, Al-Shahrour F, Cash TP, Tchkonia T, Kirkland JL, Abad M, Gros A, Arribas J, Serrano M. Chaib S, et al. Nat Cancer. 2024 Mar;5(3):448-462. doi: 10.1038/s43018-023-00712-x. Epub 2024 Jan 24. Nat Cancer. 2024. PMID: 38267628 Free PMC article.
Obesity, Senescence, and Senolytics.
Chaib S, Tchkonia T, Kirkland JL. Chaib S, et al. Handb Exp Pharmacol. 2022;274:165-180. doi: 10.1007/164_2021_555. Handb Exp Pharmacol. 2022. PMID: 34697668
Cell-cell adhesion regulates Merlin/NF2 interaction with the PAF complex.
Roehrig AE, Klupsch K, Oses-Prieto JA, Chaib S, Henderson S, Emmett W, Young LC, Surinova S, Blees A, Pfeiffer A, Tijani M, Brunk F, Hartig N, Muñoz-Alegre M, Hergovich A, Jennings BH, Burlingame AL, Rodriguez-Viciana P. Roehrig AE, et al. Among authors: chaib s. PLoS One. 2021 Aug 23;16(8):e0254697. doi: 10.1371/journal.pone.0254697. eCollection 2021. PLoS One. 2021. PMID: 34424918 Free PMC article.
A versatile drug delivery system targeting senescent cells.
Muñoz-Espín D, Rovira M, Galiana I, Giménez C, Lozano-Torres B, Paez-Ribes M, Llanos S, Chaib S, Muñoz-Martín M, Ucero AC, Garaulet G, Mulero F, Dann SG, VanArsdale T, Shields DJ, Bernardos A, Murguía JR, Martínez-Máñez R, Serrano M. Muñoz-Espín D, et al. Among authors: chaib s. EMBO Mol Med. 2018 Sep;10(9):e9355. doi: 10.15252/emmm.201809355. EMBO Mol Med. 2018. PMID: 30012580 Free PMC article.
An OFF-ON Two-Photon Fluorescent Probe for Tracking Cell Senescence in Vivo.
Lozano-Torres B, Galiana I, Rovira M, Garrido E, Chaib S, Bernardos A, Muñoz-Espín D, Serrano M, Martínez-Máñez R, Sancenón F. Lozano-Torres B, et al. Among authors: chaib s. J Am Chem Soc. 2017 Jul 5;139(26):8808-8811. doi: 10.1021/jacs.7b04985. Epub 2017 Jun 23. J Am Chem Soc. 2017. PMID: 28625064 Free article.
MATE2 Expression Is Associated with Cancer Cell Response to Metformin.
Chowdhury S, Yung E, Pintilie M, Muaddi H, Chaib S, Yeung M, Fusciello M, Sykes J, Pitcher B, Hagenkort A, McKee T, Vellanki R, Chen E, Bristow RG, Wouters BG, Koritzinsky M. Chowdhury S, et al. Among authors: chaib s. PLoS One. 2016 Dec 13;11(12):e0165214. doi: 10.1371/journal.pone.0165214. eCollection 2016. PLoS One. 2016. PMID: 27959931 Free PMC article.
Profiling microRNA expression during senescence and aging: mining for a diagnostic tool of senescent-cell burden.
Weigl M, Krammer TL, Pultar M, Wieser M, Chaib S, Suda M, Diendorfer A, Khamina-Kotisch K, Giorgadze N, Pirtskhalava T, Johnson KO, Inman CL, Xue A, Lämmermann I, Meixner B, Wang L, Xu M, Grillari R, Ogrodnik M, Tchkonia T, Hackl M, Kirkland JL, Grillari J. Weigl M, et al. Among authors: chaib s. bioRxiv [Preprint]. 2024 Apr 10:2024.04.10.588794. doi: 10.1101/2024.04.10.588794. bioRxiv. 2024. PMID: 38645053 Free PMC article. Preprint.
12 results