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Intradermal inoculations of low doses of Leishmania major and Leishmania amazonensis metacyclic promastigotes induce different immunoparasitic processes and status of protection in BALB/c mice.
Courret N, Lang T, Milon G, Antoine JC. Courret N, et al. Int J Parasitol. 2003 Oct;33(12):1373-83. doi: 10.1016/s0020-7519(03)00179-6. Int J Parasitol. 2003. PMID: 14527520
In order to simulate the natural long term parasitisms which may occur in mammals infected with Leishmania, cutaneous leishmaniases due to Leishmania major or Leishmania amazonensis were induced using a model based on the inoculation of 10-1000 metacyclic promastigotes into the e …
In order to simulate the natural long term parasitisms which may occur in mammals infected with Leishmania, cutaneous leishmaniases due to L …
Characterisation of a Leishmania mexicana knockout lacking guanosine diphosphate-mannose pyrophosphorylase.
Stewart J, Curtis J, Spurck TP, Ilg T, Garami A, Baldwin T, Courret N, McFadden GI, Davis A, Handman E. Stewart J, et al. Among authors: courret n. Int J Parasitol. 2005 Jul;35(8):861-73. doi: 10.1016/j.ijpara.2005.03.008. Int J Parasitol. 2005. PMID: 15936761
Surprisingly, in view of the lack of several known host-protective antigens, injection of the mutant parasites into BALB/c mice confers significant and long lasting protection against infection, suggesting that these temperature sensitive mutants are an attractive candidat …
Surprisingly, in view of the lack of several known host-protective antigens, injection of the mutant parasites into BALB/c mice confe …
The levels and patterns of cytokines produced by CD4 T lymphocytes of BALB/c mice infected with Leishmania major by inoculation into the ear dermis depend on the infectiousness and size of the inoculum.
Lang T, Courret N, Colle JH, Milon G, Antoine JC. Lang T, et al. Among authors: courret n. Infect Immun. 2003 May;71(5):2674-83. doi: 10.1128/IAI.71.5.2674-2683.2003. Infect Immun. 2003. PMID: 12704142 Free PMC article.
The production of cytokines by CD4 lymph node T lymphocytes derived from BALB/c mice recently infected in the ear dermis with high (10(6) parasites) or low (10(3) parasites) doses of Leishmania major metacyclic promastigotes (MP) was examined over a 3-week period following …
The production of cytokines by CD4 lymph node T lymphocytes derived from BALB/c mice recently infected in the ear dermis with high (1 …
Presentation of the Leishmania antigen LACK by infected macrophages is dependent upon the virulence of the phagocytosed parasites.
Courret N, Prina E, Mougneau E, Saraiva EM, Sacks DL, Glaichenhaus N, Antoine JC. Courret N, et al. Eur J Immunol. 1999 Mar;29(3):762-73. doi: 10.1002/(SICI)1521-4141(199903)29:03<762::AID-IMMU762>3.0.CO;2-4. Eur J Immunol. 1999. PMID: 10092078 Free article.
We have previously demonstrated that murine macrophages (Mphi) infected with Leishmania promastigotes, in contrast to Mphi infected with the amastigote stage of these parasites, are able to present the Leishmania antigen LACK (Leishmania homologue of receptors for activated C …
We have previously demonstrated that murine macrophages (Mphi) infected with Leishmania promastigotes, in contrast to Mphi infected with the …