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2009 3
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DNA damage-induced interaction between a lineage addiction oncogenic transcription factor and the MRN complex shapes a tissue-specific DNA Damage Response and cancer predisposition.
Binet R, Lambert JP, Tomkova M, Tischfield S, Baggiolini A, Picaud S, Sarkar S, Louphrasitthiphol P, Dias D, Carreira S, Humphrey T, Fillipakopoulos P, White R, Goding CR. Binet R, et al. bioRxiv [Preprint]. 2023 Apr 21:2023.04.21.537819. doi: 10.1101/2023.04.21.537819. bioRxiv. 2023. PMID: 37131595 Free PMC article. Preprint.
DNA damage remodels the MITF interactome to increase melanoma genomic instability.
Binet R, Lambert JP, Tomkova M, Tischfield S, Baggiolini A, Picaud S, Sarkar S, Louphrasitthiphol P, Dias D, Carreira S, Humphrey TC, Fillipakopoulos P, White R, Goding CR. Binet R, et al. Genes Dev. 2024 Feb 13;38(1-2):70-94. doi: 10.1101/gad.350740.123. Genes Dev. 2024. PMID: 38316520 Free PMC article.
BRN2 suppresses apoptosis, reprograms DNA damage repair, and is associated with a high somatic mutation burden in melanoma.
Herbert K, Binet R, Lambert JP, Louphrasitthiphol P, Kalkavan H, Sesma-Sanz L, Robles-Espinoza CD, Sarkar S, Suer E, Andrews S, Chauhan J, Roberts ND, Middleton MR, Gingras AC, Masson JY, Larue L, Falletta P, Goding CR. Herbert K, et al. Among authors: binet r. Genes Dev. 2019 Mar 1;33(5-6):310-332. doi: 10.1101/gad.314633.118. Epub 2019 Feb 25. Genes Dev. 2019. PMID: 30804224 Free PMC article.