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Recognition of yeast β-glucan particles triggers immunometabolic signaling required for trained immunity.
Horneck Johnston CJH, Ledwith AE, Lundahl MLE, Charles-Messance H, Hackett EE, O'Shaughnessy SD, Clegg J, Prendeville H, McGrath JP, Walsh AM, Case S, Austen Byrne H, Gautam P, Dempsey E, Corr SC, Sheedy FJ. Horneck Johnston CJH, et al. Among authors: hackett ee. iScience. 2024 Jan 26;27(3):109030. doi: 10.1016/j.isci.2024.109030. eCollection 2024 Mar 15. iScience. 2024. PMID: 38361630 Free PMC article.
von Willebrand factor links primary hemostasis to innate immunity.
Drakeford C, Aguila S, Roche F, Hokamp K, Fazavana J, Cervantes MP, Curtis AM, Hawerkamp HC, Dhami SPS, Charles-Messance H, Hackett EE, Chion A, Ward S, Ahmad A, Schoen I, Breen E, Keane J, Murphy R, Preston RJS, O'Sullivan JM, Sheedy FJ, Fallon P, O'Donnell JS. Drakeford C, et al. Among authors: hackett ee. Nat Commun. 2022 Nov 3;13(1):6320. doi: 10.1038/s41467-022-33796-7. Nat Commun. 2022. PMID: 36329021 Free PMC article.
Biomarkers Predict Relapse in Granulomatosis with Polyangiitis.
Hogan PC, O'Connell RM, Scollard S, Browne E, Hackett EE, Feighery C. Hogan PC, et al. Among authors: hackett ee. J Biomark. 2014;2014:596503. doi: 10.1155/2014/596503. Epub 2014 Apr 30. J Biomark. 2014. PMID: 26317035 Free PMC article.
β-glucans from Agaricus bisporus mushroom products drive Trained Immunity.
Case S, O'Brien T, Ledwith AE, Chen S, Horneck Johnston CJH, Hackett EE, O'Sullivan M, Charles-Messance H, Dempsey E, Yadav S, Wilson J, Corr SC, Nagar S, Sheedy FJ. Case S, et al. Among authors: hackett ee. Front Nutr. 2024 Feb 15;11:1346706. doi: 10.3389/fnut.2024.1346706. eCollection 2024. Front Nutr. 2024. PMID: 38425482 Free PMC article.