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l liese[Author]
(46 results)?
Mitochondrial morphology controls fatty acid utilization by changing CPT1 sensitivity to malonyl-CoA.
EMBO J. 2023 Jun 1;42(11):e111901. doi: 10.15252/embj.2022111901. Epub 2023 Mar 14.
EMBO J. 2023.
PMID: 36917141
Free PMC article.
Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease.
Zeng J, Acin-Perez R, Assali EA, Martin A, Brownstein AJ, Petcherski A, Fernández-Del-Rio L, Xiao R, Lo CH, Shum M, Liesa M, Han X, Shirihai OS, Grinstaff MW.
Zeng J, et al. Among authors: liesa m.
Nat Commun. 2023 May 4;14(1):2573. doi: 10.1038/s41467-023-38165-6.
Nat Commun. 2023.
PMID: 37142604
Free PMC article.
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The mitochondrial biliverdin exporter ABCB10 in hepatocytes mitigates neutrophilic inflammation in alcoholic hepatitis.
Gutierrez V, Kim-Vasquez D, Shum M, Yang Q, Dikeman D, Louie SG, Shirihai OS, Tsukamoto H, Liesa M.
Gutierrez V, et al. Among authors: liesa m.
Redox Biol. 2024 Apr;70:103052. doi: 10.1016/j.redox.2024.103052. Epub 2024 Jan 24.
Redox Biol. 2024.
PMID: 38290384
Free PMC article.
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ABCB10 exports mitochondrial biliverdin, driving metabolic maladaptation in obesity.
Shum M, Shintre CA, Althoff T, Gutierrez V, Segawa M, Saxberg AD, Martinez M, Adamson R, Young MR, Faust B, Gharakhanian R, Su S, Chella Krishnan K, Mahdaviani K, Veliova M, Wolf DM, Ngo J, Nocito L, Stiles L, Abramson J, Lusis AJ, Hevener AL, Zoghbi ME, Carpenter EP, Liesa M.
Shum M, et al. Among authors: liesa m.
Sci Transl Med. 2021 May 19;13(594):eabd1869. doi: 10.1126/scitranslmed.abd1869.
Sci Transl Med. 2021.
PMID: 34011630
Free PMC article.
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Bactericidal antibiotics induce mitochondrial dysfunction and oxidative damage in Mammalian cells.
Kalghatgi S, Spina CS, Costello JC, Liesa M, Morones-Ramirez JR, Slomovic S, Molina A, Shirihai OS, Collins JJ.
Kalghatgi S, et al. Among authors: liesa m.
Sci Transl Med. 2013 Jul 3;5(192):192ra85. doi: 10.1126/scitranslmed.3006055.
Sci Transl Med. 2013.
PMID: 23825301
Free PMC article.
The deleterious effects of bactericidal antibiotics were alleviated in cell culture and in mice by the administration of the antioxidant N-acetyl-l-cysteine or prevented by preferential use of bacteriostatic antibiotics. ...
The deleterious effects of bactericidal antibiotics were alleviated in cell culture and in mice by the administration of the antioxidant N-a …
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Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet-Induced Metabolic Heart Disease.
Sverdlov AL, Elezaby A, Qin F, Behring JB, Luptak I, Calamaras TD, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Bachschmid MM, Colucci WS.
Sverdlov AL, et al. Among authors: liesa m.
J Am Heart Assoc. 2016 Jan 11;5(1):e002555. doi: 10.1161/JAHA.115.002555.
J Am Heart Assoc. 2016.
PMID: 26755553
Free PMC article.
In HFHS-fed wild-type mice complex II substrate-driven ATP synthesis and activity were restored ex vivo by dithiothreitol (5 mmol/L), suggesting a role for reversible cysteine oxidative posttranslational modifications. ...
In HFHS-fed wild-type mice complex II substrate-driven ATP synthesis and activity were restored ex vivo by dithiothreitol (5 mmol/L), …
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