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Allele-Specific Knockdown of Mutant Huntingtin Protein via Editing at Coding Region Single Nucleotide Polymorphism Heterozygosities.
Oikemus SR, Pfister EL, Sapp E, Chase KO, Kennington LA, Hudgens E, Miller R, Zhu LJ, Chaudhary A, Mick EO, Sena-Esteves M, Wolfe SA, DiFiglia M, Aronin N, Brodsky MH. Oikemus SR, et al. Among authors: kennington la. Hum Gene Ther. 2022 Jan;33(1-2):25-36. doi: 10.1089/hum.2020.323. Hum Gene Ther. 2022. PMID: 34376056 Free PMC article.
Increased Steady-State Mutant Huntingtin mRNA in Huntington's Disease Brain.
Liu W, Chaurette J, Pfister EL, Kennington LA, Chase KO, Bullock J, Vonsattel JP, Faull RL, Macdonald D, DiFiglia M, Zamore PD, Aronin N. Liu W, et al. Among authors: kennington la. J Huntingtons Dis. 2013;2(4):491-500. doi: 10.3233/JHD-130079. J Huntingtons Dis. 2013. PMID: 25062733
Artificial miRNAs Reduce Human Mutant Huntingtin Throughout the Striatum in a Transgenic Sheep Model of Huntington's Disease.
Pfister EL, DiNardo N, Mondo E, Borel F, Conroy F, Fraser C, Gernoux G, Han X, Hu D, Johnson E, Kennington L, Liu P, Reid SJ, Sapp E, Vodicka P, Kuchel T, Morton AJ, Howland D, Moser R, Sena-Esteves M, Gao G, Mueller C, DiFiglia M, Aronin N. Pfister EL, et al. Among authors: kennington l. Hum Gene Ther. 2018 Jun;29(6):663-673. doi: 10.1089/hum.2017.199. Epub 2018 Feb 23. Hum Gene Ther. 2018. PMID: 29207890 Free PMC article.
Linking SNPs to CAG repeat length in Huntington's disease patients.
Liu W, Kennington LA, Rosas HD, Hersch S, Cha JH, Zamore PD, Aronin N. Liu W, et al. Among authors: kennington la. Nat Methods. 2008 Nov;5(11):951-3. doi: 10.1038/nmeth.1261. Epub 2008 Oct 19. Nat Methods. 2008. PMID: 18931668 Free PMC article.
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