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aihua deng[Author]
(79 results)?
Degradation of Hexokinase 2 Blocks Glycolysis and Induces GSDME-Dependent Pyroptosis to Amplify Immunogenic Cell Death for Breast Cancer Therapy.
J Med Chem. 2023 Jul 13;66(13):8464-8483. doi: 10.1021/acs.jmedchem.3c00118. Epub 2023 Jun 27.
J Med Chem. 2023.
PMID: 37376788
A novel mitochondria-targeting DHODH inhibitor induces robust ferroptosis and alleviates immune suppression.
Hai Y, Fan R, Zhao T, Lin R, Zhuang J, Deng A, Meng S, Hou Z, Wei G.
Hai Y, et al. Among authors: deng a.
Pharmacol Res. 2024 Apr;202:107115. doi: 10.1016/j.phrs.2024.107115. Epub 2024 Feb 27.
Pharmacol Res. 2024.
PMID: 38423231
Free article.
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Novel Pt(IV) complex OAP2 induces STING activation and pyroptosis via mitochondrial membrane remodeling for synergistic chemo-immunotherapy.
Fan R, Lin R, Zhang S, Deng A, Hai Y, Zhuang J, Liu Y, Cheng M, Wei G.
Fan R, et al. Among authors: deng a.
Acta Pharm Sin B. 2024 Apr;14(4):1742-1758. doi: 10.1016/j.apsb.2023.11.032. Epub 2023 Dec 16.
Acta Pharm Sin B. 2024.
PMID: 38572099
Free PMC article.
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CJ2: A Novel Potent Platinum(IV) Prodrug Enhances Chemo-Immunotherapy by Facilitating PD-L1 Degradation in the Cytoplasm and Cytomembrane.
Fan R, Deng A, Qi B, Zhang S, Sang R, Luo L, Gou J, Liu Y, Lin R, Zhao M, Liu Y, Yang L, Cheng M, Wei G.
Fan R, et al. Among authors: deng a.
J Med Chem. 2023 Jan 12;66(1):875-889. doi: 10.1021/acs.jmedchem.2c01719. Epub 2023 Jan 3.
J Med Chem. 2023.
PMID: 36594812
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A platinum(IV)-artesunate complex triggers ferroptosis by boosting cytoplasmic and mitochondrial lipid peroxidation to enhance tumor immunotherapy.
Fan R, Deng A, Lin R, Zhang S, Cheng C, Zhuang J, Hai Y, Zhao M, Yang L, Wei G.
Fan R, et al. Among authors: deng a.
MedComm (2020). 2024 May 20;5(6):e570. doi: 10.1002/mco2.570. eCollection 2024 Jun.
MedComm (2020). 2024.
PMID: 38774917
Free PMC article.
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