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LXR directly regulates glycosphingolipid synthesis and affects human CD4+ T cell function.
Waddington KE, Robinson GA, Rubio-Cuesta B, Chrifi-Alaoui E, Andreone S, Poon KS, Ivanova I, Martin-Gutierrez L, Owen DM, Jury EC, Pineda-Torra I. Waddington KE, et al. Among authors: martin gutierrez l. Proc Natl Acad Sci U S A. 2021 May 25;118(21):e2017394118. doi: 10.1073/pnas.2017394118. Proc Natl Acad Sci U S A. 2021. PMID: 34006637 Free PMC article.
Impaired LXRα Phosphorylation Attenuates Progression of Fatty Liver Disease.
Becares N, Gage MC, Voisin M, Shrestha E, Martin-Gutierrez L, Liang N, Louie R, Pourcet B, Pello OM, Luong TV, Goñi S, Pichardo-Almarza C, Røberg-Larsen H, Diaz-Zuccarini V, Steffensen KR, O'Brien A, Garabedian MJ, Rombouts K, Treuter E, Pineda-Torra I. Becares N, et al. Among authors: martin gutierrez l. Cell Rep. 2019 Jan 22;26(4):984-995.e6. doi: 10.1016/j.celrep.2018.12.094. Cell Rep. 2019. PMID: 30673619 Free PMC article.
COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study.
Manson JJ, Crooks C, Naja M, Ledlie A, Goulden B, Liddle T, Khan E, Mehta P, Martin-Gutierrez L, Waddington KE, Robinson GA, Ribeiro Santos L, McLoughlin E, Snell A, Adeney C, Schim van der Loeff I, Baker KF, Duncan CJA, Hanrath AT, Lendrem BC, De Soyza A, Peng J, J'Bari H, Greenwood M, Hawkins E, Peckham H, Marks M, Rampling T, Luintel A, Williams B, Brown M, Singer M, West J, Jury EC, Collin M, Tattersall RS. Manson JJ, et al. Among authors: martin gutierrez l. Lancet Rheumatol. 2020 Oct;2(10):e594-e602. doi: 10.1016/S2665-9913(20)30275-7. Epub 2020 Aug 21. Lancet Rheumatol. 2020. PMID: 32864628 Free PMC article.
Stratification of Patients With Sjögren's Syndrome and Patients With Systemic Lupus Erythematosus According to Two Shared Immune Cell Signatures, With Potential Therapeutic Implications.
Martin-Gutierrez L, Peng J, Thompson NL, Robinson GA, Naja M, Peckham H, Wu W, J'bari H, Ahwireng N, Waddington KE, Bradford CM, Varnier G, Gandhi A, Radmore R, Gupta V, Isenberg DA, Jury EC, Ciurtin C. Martin-Gutierrez L, et al. Arthritis Rheumatol. 2021 Sep;73(9):1626-1637. doi: 10.1002/art.41708. Epub 2021 Aug 6. Arthritis Rheumatol. 2021. PMID: 33645922