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Human cytomegalovirus degrades DMXL1 to inhibit autophagy, lysosomal acidification, and viral assembly.
Li H, Fletcher-Etherington A, Hunter LM, Keshri S, Fielding CA, Nightingale K, Ravenhill B, Nobre L, Potts M, Antrobus R, Crump CM, Rubinsztein DC, Stanton RJ, Weekes MP. Li H, et al. Among authors: hunter lm. Cell Host Microbe. 2024 Apr 10;32(4):466-478.e11. doi: 10.1016/j.chom.2024.02.013. Epub 2024 Mar 12. Cell Host Microbe. 2024. PMID: 38479395 Free article.
Human cytomegalovirus protein RL1 degrades the antiviral factor SLFN11 via recruitment of the CRL4 E3 ubiquitin ligase complex.
Nightingale K, Potts M, Hunter LM, Fielding CA, Zerbe CM, Fletcher-Etherington A, Nobre L, Wang ECY, Strang BL, Houghton JW, Antrobus R, Suarez NM, Nichols J, Davison AJ, Stanton RJ, Weekes MP. Nightingale K, et al. Among authors: hunter lm. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2108173119. doi: 10.1073/pnas.2108173119. Proc Natl Acad Sci U S A. 2022. PMID: 35105802 Free PMC article.