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Page 1
Optimization of AsCas12a for combinatorial genetic screens in human cells.
Nat Biotechnol. 2021 Jan;39(1):94-104. doi: 10.1038/s41587-020-0600-6. Epub 2020 Jul 13.
Nat Biotechnol. 2021.
PMID: 32661438
Free PMC article.
Optimization of Cas12a for multiplexed genome-scale transcriptional activation.
Griffith AL, Zheng F, McGee AV, Miller NW, Szegletes ZM, Reint G, Gademann F, Nwolah I, Hegde M, Liu YV, Goodale A, Doench JG.
Griffith AL, et al.
Cell Genom. 2023 Sep 1;3(9):100387. doi: 10.1016/j.xgen.2023.100387. eCollection 2023 Sep 13.
Cell Genom. 2023.
PMID: 37719144
Free PMC article.
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Modular vector assembly enables rapid assessment of emerging CRISPR technologies.
McGee AV, Liu YV, Griffith AL, Szegletes ZM, Wen B, Kraus C, Miller NW, Steger RJ, Velasco BE, Bosch JA, Zirin JD, Viswanatha R, Sontheimer EJ, Goodale A, Greene MA, Green TM, Doench JG.
McGee AV, et al. Among authors: griffith al.
bioRxiv [Preprint]. 2023 Oct 27:2023.10.25.564061. doi: 10.1101/2023.10.25.564061.
bioRxiv. 2023.
PMID: 37961518
Free PMC article.
Updated.
Preprint.
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Benchmarking of SpCas9 variants enables deeper base editor screens of BRCA1 and BCL2.
Sangree AK, Griffith AL, Szegletes ZM, Roy P, DeWeirdt PC, Hegde M, McGee AV, Hanna RE, Doench JG.
Sangree AK, et al. Among authors: griffith al.
Nat Commun. 2022 Mar 14;13(1):1318. doi: 10.1038/s41467-022-28884-7.
Nat Commun. 2022.
PMID: 35288574
Free PMC article.
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Modular vector assembly enables rapid assessment of emerging CRISPR technologies.
McGee AV, Liu YV, Griffith AL, Szegletes ZM, Wen B, Kraus C, Miller NW, Steger RJ, Escude Velasco B, Bosch JA, Zirin JD, Viswanatha R, Sontheimer EJ, Goodale A, Greene MA, Green TM, Doench JG.
McGee AV, et al. Among authors: griffith al.
Cell Genom. 2024 Mar 13;4(3):100519. doi: 10.1016/j.xgen.2024.100519.
Cell Genom. 2024.
PMID: 38484704
Free PMC article.
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Discovery of putative tumor suppressors from CRISPR screens reveals rewired lipid metabolism in acute myeloid leukemia cells.
Lenoir WF, Morgado M, DeWeirdt PC, McLaughlin M, Griffith AL, Sangree AK, Feeley MN, Esmaeili Anvar N, Kim E, Bertolet LL, Colic M, Dede M, Doench JG, Hart T.
Lenoir WF, et al. Among authors: griffith al.
Nat Commun. 2021 Nov 11;12(1):6506. doi: 10.1038/s41467-021-26867-8.
Nat Commun. 2021.
PMID: 34764293
Free PMC article.
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