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A simultaneous knockout knockin genome editing strategy in HSPCs potently inhibits CCR5- and CXCR4-tropic HIV-1 infection.
Cell Stem Cell. 2024 Apr 4;31(4):499-518.e6. doi: 10.1016/j.stem.2024.03.002.
Cell Stem Cell. 2024.
PMID: 38579682
Combining Cell-Intrinsic and -Extrinsic Resistance to HIV-1 By Engineering Hematopoietic Stem Cells for CCR5 Knockout and B Cell Secretion of Therapeutic Antibodies.
Feist WN, Luna SE, Ben-Efraim K, Filsinger Interrante MV, Amorin NA, Johnston NM, Bruun TUJ, Ghanim HY, Lesch BJ, Dudek AM, Porteus MH.
Feist WN, et al. Among authors: ben efraim k.
bioRxiv [Preprint]. 2024 Mar 9:2024.03.08.583956. doi: 10.1101/2024.03.08.583956.
bioRxiv. 2024.
PMID: 38496600
Free PMC article.
Preprint.
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