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william h frist[Author]
(17 results)?
High-efficiency transgene integration by homology-directed repair in human primary cells using DNA-PKcs inhibition.
Nat Biotechnol. 2024 May;42(5):731-744. doi: 10.1038/s41587-023-01888-4. Epub 2023 Aug 3.
Nat Biotechnol. 2024.
PMID: 37537500
A simultaneous knockout knockin genome editing strategy in HSPCs potently inhibits CCR5- and CXCR4-tropic HIV-1 infection.
Dudek AM, Feist WN, Sasu EJ, Luna SE, Ben-Efraim K, Bak RO, Cepika AM, Porteus MH.
Dudek AM, et al. Among authors: feist wn.
Cell Stem Cell. 2024 Apr 4;31(4):499-518.e6. doi: 10.1016/j.stem.2024.03.002.
Cell Stem Cell. 2024.
PMID: 38579682
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Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells.
Baik R, Cromer MK, Glenn SE, Vakulskas CA, Chmielewski KO, Dudek AM, Feist WN, Klermund J, Shipp S, Cathomen T, Dever DP, Porteus MH.
Baik R, et al. Among authors: feist wn.
Nat Commun. 2024 Jan 2;15(1):111. doi: 10.1038/s41467-023-43413-w.
Nat Commun. 2024.
PMID: 38169468
Free PMC article.
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S-MiRAGE: A Quantitative, Secreted RNA-Based Reporter of Gene Expression and Cell Persistence.
Mitra K, Feist WN, Anfossi S, Fuentes-Mattei E, Almeida MI, Kim JJ, Calin GA, Warmflash A.
Mitra K, et al. Among authors: feist wn.
ACS Synth Biol. 2019 Jan 18;8(1):25-33. doi: 10.1021/acssynbio.8b00406. Epub 2018 Dec 21.
ACS Synth Biol. 2019.
PMID: 30550267
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Combining Cell-Intrinsic and -Extrinsic Resistance to HIV-1 By Engineering Hematopoietic Stem Cells for CCR5 Knockout and B Cell Secretion of Therapeutic Antibodies.
Feist WN, Luna SE, Ben-Efraim K, Filsinger Interrante MV, Amorin NA, Johnston NM, Bruun TUJ, Ghanim HY, Lesch BJ, Dudek AM, Porteus MH.
Feist WN, et al.
bioRxiv [Preprint]. 2024 Mar 9:2024.03.08.583956. doi: 10.1101/2024.03.08.583956.
bioRxiv. 2024.
PMID: 38496600
Free PMC article.
Preprint.
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