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Modeling transcriptomic age using knowledge-primed artificial neural networks.
Holzscheck N, Falckenhayn C, Söhle J, Kristof B, Siegner R, Werner A, Schössow J, Jürgens C, Völzke H, Wenck H, Winnefeld M, Grönniger E, Kaderali L. Holzscheck N, et al. Among authors: siegner r. NPJ Aging Mech Dis. 2021 Jun 1;7(1):15. doi: 10.1038/s41514-021-00068-5. NPJ Aging Mech Dis. 2021. PMID: 34075044 Free PMC article.
Topical treatment with coenzyme Q10-containing formulas improves skin's Q10 level and provides antioxidative effects.
Knott A, Achterberg V, Smuda C, Mielke H, Sperling G, Dunckelmann K, Vogelsang A, Krüger A, Schwengler H, Behtash M, Kristof S, Diekmann H, Eisenberg T, Berroth A, Hildebrand J, Siegner R, Winnefeld M, Teuber F, Fey S, Möbius J, Retzer D, Burkhardt T, Lüttke J, Blatt T. Knott A, et al. Among authors: siegner r. Biofactors. 2015 Nov-Dec;41(6):383-90. doi: 10.1002/biof.1239. Epub 2015 Dec 9. Biofactors. 2015. PMID: 26648450 Free PMC article.
Identification of dihydromyricetin as a natural DNA methylation inhibitor with rejuvenating activity in human skin.
Falckenhayn C, Bienkowska A, Söhle J, Wegner K, Raddatz G, Kristof B, Kuck D, Siegner R, Kaufmann R, Korn J, Baumann S, Lange D, Schepky A, Völzke H, Kaderali L, Winnefeld M, Lyko F, Grönniger E. Falckenhayn C, et al. Among authors: siegner r. Front Aging. 2024 Mar 4;4:1258184. doi: 10.3389/fragi.2023.1258184. eCollection 2023. Front Aging. 2024. PMID: 38500495 Free PMC article.