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Page 1
Cooperation and Interplay between EGFR Signalling and Extracellular Vesicle Biogenesis in Cancer.
Cells. 2020 Dec 8;9(12):2639. doi: 10.3390/cells9122639.
Cells. 2020.
PMID: 33302515
Free PMC article.
Review.
A functional SUMO-motif in the active site of PIM1 promotes its degradation via RNF4, and stimulates protein kinase activity.
Iyer RS, Chatham L, Sleigh R, Meek DW.
Iyer RS, et al.
Sci Rep. 2017 Jun 15;7(1):3598. doi: 10.1038/s41598-017-03775-w.
Sci Rep. 2017.
PMID: 28620180
Free PMC article.
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Drug-resistant EGFR mutations promote lung cancer by stabilizing interfaces in ligand-free kinase-active EGFR oligomers.
Iyer RS, Needham SR, Galdadas I, Davis BM, Roberts SK, Man RCH, Zanetti-Domingues LC, Clarke DT, Fruhwirth GO, Parker PJ, Rolfe DJ, Gervasio FL, Martin-Fernandez ML.
Iyer RS, et al.
Nat Commun. 2024 Mar 19;15(1):2130. doi: 10.1038/s41467-024-46284-x.
Nat Commun. 2024.
PMID: 38503739
Free PMC article.
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The RNA helicase/transcriptional co-regulator, p68 (DDX5), stimulates expression of oncogenic protein kinase, Polo-like kinase-1 (PLK1), and is associated with elevated PLK1 levels in human breast cancers.
Iyer RS, Nicol SM, Quinlan PR, Thompson AM, Meek DW, Fuller-Pace FV.
Iyer RS, et al.
Cell Cycle. 2014;13(9):1413-23. doi: 10.4161/cc.28415. Epub 2014 Mar 6.
Cell Cycle. 2014.
PMID: 24626184
Free PMC article.
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