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ICOS ligand and IL-10 synergize to promote host-microbiota mutualism.
Landuyt AE, Klocke BJ, Duck LW, Kemp KM, Muir RQ, Jennings MS, Blum SI, Tse HM, Lee G, Morrow CD, Elson CO, Maynard CL. Landuyt AE, et al. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2018278118. doi: 10.1073/pnas.2018278118. Proc Natl Acad Sci U S A. 2021. PMID: 33753483 Free PMC article.
GNTI-122: an autologous antigen-specific engineered Treg cell therapy for type 1 diabetes.
Uenishi GI, Repic M, Yam JY, Landuyt A, Saikumar-Lakshmi P, Guo T, Zarin P, Sassone-Corsi M, Chicoine A, Kellogg H, Hunt M, Drow T, Tewari R, Cook PJ, Yang SJ, Cerosaletti K, Schweinoch D, Guiastrennec B, James E, Patel C, Chen TF, Buckner JH, Rawlings DJ, Wickham TJ, Mueller KT. Uenishi GI, et al. Among authors: landuyt a. JCI Insight. 2024 Feb 8;9(6):e171844. doi: 10.1172/jci.insight.171844. JCI Insight. 2024. PMID: 38516892 Free PMC article.
Bone marrow Tregs mediate stromal cell function and support hematopoiesis via IL-10.
Camacho V, Matkins VR, Patel SB, Lever JM, Yang Z, Ying L, Landuyt AE, Dean EC, George JF, Yang H, Ferrell PB, Maynard CL, Weaver CT, Turnquist HR, Welner RS. Camacho V, et al. Among authors: landuyt ae. JCI Insight. 2020 Nov 19;5(22):e135681. doi: 10.1172/jci.insight.135681. JCI Insight. 2020. PMID: 33208555 Free PMC article.