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Childhood cancer mutagenesis caused by transposase-derived PGBD5.
Yamada M, Keller RR, Gutierrez RL, Cameron D, Suzuki H, Sanghrajka R, Vaynshteyn J, Gerwin J, Maura F, Hooper W, Shah M, Robine N, Demarest P, Bayin NS, Zapater LJ, Reed C, Hébert S, Masilionis I, Chaligne R, Socci ND, Taylor MD, Kleinman CL, Joyner AL, Raju GP, Kentsis A. Yamada M, et al. Among authors: sanghrajka r. Sci Adv. 2024 Mar 22;10(12):eadn4649. doi: 10.1126/sciadv.adn4649. Epub 2024 Mar 22. Sci Adv. 2024. PMID: 38517960 Free PMC article.
Thyroid Progenitors Are Robustly Derived from Embryonic Stem Cells through Transient, Developmental Stage-Specific Overexpression of Nkx2-1.
Dame K, Cincotta S, Lang AH, Sanghrajka RM, Zhang L, Choi J, Kwok L, Wilson T, Kańduła MM, Monti S, Hollenberg AN, Mehta P, Kotton DN, Ikonomou L. Dame K, et al. Among authors: sanghrajka rm. Stem Cell Reports. 2017 Feb 14;8(2):216-225. doi: 10.1016/j.stemcr.2016.12.024. Epub 2017 Feb 2. Stem Cell Reports. 2017. PMID: 28162994 Free PMC article.
The in vivo genetic program of murine primordial lung epithelial progenitors.
Ikonomou L, Herriges MJ, Lewandowski SL, Marsland R 3rd, Villacorta-Martin C, Caballero IS, Frank DB, Sanghrajka RM, Dame K, Kańduła MM, Hicks-Berthet J, Lawton ML, Christodoulou C, Fabian AJ, Kolaczyk E, Varelas X, Morrisey EE, Shannon JM, Mehta P, Kotton DN. Ikonomou L, et al. Among authors: sanghrajka rm. Nat Commun. 2020 Jan 31;11(1):635. doi: 10.1038/s41467-020-14348-3. Nat Commun. 2020. PMID: 32005814 Free PMC article.
CSF1R inhibition depletes tumor-associated macrophages and attenuates tumor progression in a mouse sonic Hedgehog-Medulloblastoma model.
Tan IL, Arifa RDN, Rallapalli H, Kana V, Lao Z, Sanghrajka RM, Sumru Bayin N, Tanne A, Wojcinski A, Korshunov A, Bhardwaj N, Merad M, Turnbull DH, Lafaille JJ, Joyner AL. Tan IL, et al. Among authors: sanghrajka rm. Oncogene. 2021 Jan;40(2):396-407. doi: 10.1038/s41388-020-01536-0. Epub 2020 Nov 6. Oncogene. 2021. PMID: 33159168 Free PMC article.
Lateral cerebellum is preferentially sensitive to high sonic hedgehog signaling and medulloblastoma formation.
Tan IL, Wojcinski A, Rallapalli H, Lao Z, Sanghrajka RM, Stephen D, Volkova E, Korshunov A, Remke M, Taylor MD, Turnbull DH, Joyner AL. Tan IL, et al. Among authors: sanghrajka rm. Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3392-3397. doi: 10.1073/pnas.1717815115. Epub 2018 Mar 12. Proc Natl Acad Sci U S A. 2018. PMID: 29531057 Free PMC article.