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Spatiotemporal dynamics of SETD5-containing NCoR-HDAC3 complex determines enhancer activation for adipogenesis.
Matsumura Y, Ito R, Yajima A, Yamaguchi R, Tanaka T, Kawamura T, Magoori K, Abe Y, Uchida A, Yoneshiro T, Hirakawa H, Zhang J, Arai M, Yang C, Yang G, Takahashi H, Fujihashi H, Nakaki R, Yamamoto S, Ota S, Tsutsumi S, Inoue SI, Kimura H, Wada Y, Kodama T, Inagaki T, Osborne TF, Aburatani H, Node K, Sakai J. Matsumura Y, et al. Among authors: uchida a. Nat Commun. 2021 Dec 2;12(1):7045. doi: 10.1038/s41467-021-27321-5. Nat Commun. 2021. PMID: 34857762 Free PMC article.
MYPT1-PP1β phosphatase negatively regulates both chromatin landscape and co-activator recruitment for beige adipogenesis.
Takahashi H, Yang G, Yoneshiro T, Abe Y, Ito R, Yang C, Nakazono J, Okamoto-Katsuyama M, Uchida A, Arai M, Jin H, Choi H, Tumenjargal M, Xie S, Zhang J, Sagae H, Zhao Y, Yamaguchi R, Nomura Y, Shimizu Y, Yamada K, Yasuda S, Kimura H, Tanaka T, Wada Y, Kodama T, Aburatani H, Zhu MS, Inagaki T, Osborne TF, Kawamura T, Ishihama Y, Matsumura Y, Sakai J. Takahashi H, et al. Among authors: uchida a. Nat Commun. 2022 Sep 29;13(1):5715. doi: 10.1038/s41467-022-33363-0. Nat Commun. 2022. PMID: 36175407 Free PMC article.
Mitochondrial biogenesis in white adipose tissue mediated by JMJD1A-PGC-1 axis limits age-related metabolic disease.
Ito R, Xie S, Tumenjargal M, Sugahara Y, Yang C, Takahashi H, Arai M, Inoue SI, Uchida A, Nakano K, Choi H, Yang G, Zhao Y, Yamaguchi R, Jin H, Sagae H, Wada Y, Tanaka T, Kimura H, Kodama T, Aburatani H, Takeda K, Inagaki T, Osborne TF, Yoneshiro T, Matsumura Y, Sakai J. Ito R, et al. Among authors: uchida a. iScience. 2024 Mar 1;27(4):109398. doi: 10.1016/j.isci.2024.109398. eCollection 2024 Apr 19. iScience. 2024. PMID: 38544573 Free PMC article.
COUP-TFII acts downstream of Wnt/beta-catenin signal to silence PPARgamma gene expression and repress adipogenesis.
Okamura M, Kudo H, Wakabayashi K, Tanaka T, Nonaka A, Uchida A, Tsutsumi S, Sakakibara I, Naito M, Osborne TF, Hamakubo T, Ito S, Aburatani H, Yanagisawa M, Kodama T, Sakai J. Okamura M, et al. Among authors: uchida a. Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5819-24. doi: 10.1073/pnas.0901676106. Epub 2009 Mar 23. Proc Natl Acad Sci U S A. 2009. PMID: 19307559 Free PMC article.
Cooperative interaction between hepatocyte nuclear factor 4 alpha and GATA transcription factors regulates ATP-binding cassette sterol transporters ABCG5 and ABCG8.
Sumi K, Tanaka T, Uchida A, Magoori K, Urashima Y, Ohashi R, Ohguchi H, Okamura M, Kudo H, Daigo K, Maejima T, Kojima N, Sakakibara I, Jiang S, Hasegawa G, Kim I, Osborne TF, Naito M, Gonzalez FJ, Hamakubo T, Kodama T, Sakai J. Sumi K, et al. Among authors: uchida a. Mol Cell Biol. 2007 Jun;27(12):4248-60. doi: 10.1128/MCB.01894-06. Epub 2007 Apr 2. Mol Cell Biol. 2007. PMID: 17403900 Free PMC article.
SOX6 attenuates glucose-stimulated insulin secretion by repressing PDX1 transcriptional activity and is down-regulated in hyperinsulinemic obese mice.
Iguchi H, Ikeda Y, Okamura M, Tanaka T, Urashima Y, Ohguchi H, Takayasu S, Kojima N, Iwasaki S, Ohashi R, Jiang S, Hasegawa G, Ioka RX, Magoori K, Sumi K, Maejima T, Uchida A, Naito M, Osborne TF, Yanagisawa M, Yamamoto TT, Kodama T, Sakai J. Iguchi H, et al. Among authors: uchida a. J Biol Chem. 2005 Nov 11;280(45):37669-80. doi: 10.1074/jbc.M505392200. Epub 2005 Sep 7. J Biol Chem. 2005. PMID: 16148004 Free article.
Hepatocyte nuclear factor 4alpha contributes to thyroid hormone homeostasis by cooperatively regulating the type 1 iodothyronine deiodinase gene with GATA4 and Kruppel-like transcription factor 9.
Ohguchi H, Tanaka T, Uchida A, Magoori K, Kudo H, Kim I, Daigo K, Sakakibara I, Okamura M, Harigae H, Sasaki T, Osborne TF, Gonzalez FJ, Hamakubo T, Kodama T, Sakai J. Ohguchi H, et al. Among authors: uchida a. Mol Cell Biol. 2008 Jun;28(12):3917-31. doi: 10.1128/MCB.02154-07. Epub 2008 Apr 21. Mol Cell Biol. 2008. PMID: 18426912 Free PMC article.