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MYCN drives oncogenesis by cooperating with the histone methyltransferase G9a and the WDR5 adaptor to orchestrate global gene transcription.
PLoS Biol. 2024 Mar 28;22(3):e3002240. doi: 10.1371/journal.pbio.3002240. eCollection 2024 Mar.
PLoS Biol. 2024.
PMID: 38547242
Free PMC article.
MYCN driven oncogenesis involves cooperation with WDR5 to activate canonical MYC targets and G9a to repress differentiation genes.
Liu Z, Zhang X, Xu M, Hong JJ, Ciardiello A, Lei H, Shern JF, Thiele CJ.
Liu Z, et al. Among authors: hong jj.
bioRxiv [Preprint]. 2023 Jul 12:2023.07.11.548643. doi: 10.1101/2023.07.11.548643.
bioRxiv. 2023.
PMID: 37781575
Free PMC article.
Preprint.
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