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Page 1
TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways.
Wang S, Sudan R, Peng V, Zhou Y, Du S, Yuede CM, Lei T, Hou J, Cai Z, Cella M, Nguyen K, Poliani PL, Beatty WL, Chen Y, Cao S, Lin K, Rodrigues C, Ellebedy AH, Gilfillan S, Brown GD, Holtzman DM, Brioschi S, Colonna M. Wang S, et al. Among authors: lin k. Cell. 2022 Oct 27;185(22):4153-4169.e19. doi: 10.1016/j.cell.2022.09.033. Cell. 2022. PMID: 36306735 Free PMC article.
Antibody-mediated targeting of human microglial leukocyte Ig-like receptor B4 attenuates amyloid pathology in a mouse model.
Hou J, Chen Y, Cai Z, Heo GS, Yuede CM, Wang Z, Lin K, Saadi F, Trsan T, Nguyen AT, Constantopoulos E, Larsen RA, Zhu Y, Wagner ND, McLaughlin N, Kuang XC, Barrow AD, Li D, Zhou Y, Wang S, Gilfillan S, Gross ML, Brioschi S, Liu Y, Holtzman DM, Colonna M. Hou J, et al. Among authors: lin k. Sci Transl Med. 2024 Apr 3;16(741):eadj9052. doi: 10.1126/scitranslmed.adj9052. Epub 2024 Apr 3. Sci Transl Med. 2024. PMID: 38569016
Targeting tauopathy with engineered tau-degrading intrabodies.
Gallardo G, Wong CH, Ricardez SM, Mann CN, Lin KH, Leyns CEG, Jiang H, Holtzman DM. Gallardo G, et al. Among authors: lin kh. Mol Neurodegener. 2019 Oct 22;14(1):38. doi: 10.1186/s13024-019-0340-6. Mol Neurodegener. 2019. PMID: 31640765 Free PMC article.
11 results