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RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells.
Nucleic Acids Res. 2023 Oct 27;51(19):10484-10505. doi: 10.1093/nar/gkad733.
Nucleic Acids Res. 2023.
PMID: 37697435
Free PMC article.
C-terminus of Hsp70 Interacting Protein (CHIP) and Neurodegeneration: Lessons from the Bench and Bedside.
Mylvaganam S, Earnshaw R, Heymann G, Kalia SK, Kalia LV.
Mylvaganam S, et al. Among authors: earnshaw r.
Curr Neuropharmacol. 2021;19(7):1038-1068. doi: 10.2174/1570159X18666201116145507.
Curr Neuropharmacol. 2021.
PMID: 33200713
Free PMC article.
Review.
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Bcl-2-associated athanogene 5 (BAG5) regulates Parkin-dependent mitophagy and cell death.
De Snoo ML, Friesen EL, Zhang YT, Earnshaw R, Dorval G, Kapadia M, O'Hara DM, Agapova V, Chau H, Pellerito O, Tang MY, Wang X, Schmitt-Ulms G, Durcan TM, Fon EA, Kalia LV, Kalia SK.
De Snoo ML, et al. Among authors: earnshaw r.
Cell Death Dis. 2019 Dec 2;10(12):907. doi: 10.1038/s41419-019-2132-x.
Cell Death Dis. 2019.
PMID: 31787745
Free PMC article.
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BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62.
Friesen EL, Zhang YT, Earnshaw R, De Snoo ML, O'Hara DM, Agapova V, Chau H, Ngana S, Chen KS, Kalia LV, Kalia SK.
Friesen EL, et al. Among authors: earnshaw r.
Front Cell Dev Biol. 2020 Aug 4;8:716. doi: 10.3389/fcell.2020.00716. eCollection 2020.
Front Cell Dev Biol. 2020.
PMID: 32850835
Free PMC article.
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Mitophagy Upregulation Occurs Early in the Neurodegenerative Process Mediated by α-Synuclein.
Hui S, George J, Kapadia M, Chau H, Bariring Z, Earnshaw R, Shafiq K, Kalia LV, Kalia SK.
Hui S, et al. Among authors: earnshaw r.
Mol Neurobiol. 2024 Apr 6. doi: 10.1007/s12035-024-04131-6. Online ahead of print.
Mol Neurobiol. 2024.
PMID: 38581539
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