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Metformin-induced reductions in tumor growth involves modulation of the gut microbiome.
Broadfield LA, Saigal A, Szamosi JC, Hammill JA, Bezverbnaya K, Wang D, Gautam J, Tsakiridis EE, Di Pastena F, McNicol J, Wu J, Syed S, Lally JSV, Raphenya AR, Blouin MJ, Pollak M, Sacconi A, Blandino G, McArthur AG, Schertzer JD, Surette MG, Collins SM, Bramson JL, Muti P, Tsakiridis T, Steinberg GR. Broadfield LA, et al. Among authors: mcnicol j. Mol Metab. 2022 Jul;61:101498. doi: 10.1016/j.molmet.2022.101498. Epub 2022 Apr 20. Mol Metab. 2022. PMID: 35452877 Free PMC article.
Lineage-Specific Differentiation Is Influenced by State of Human Pluripotency.
Lee JH, Laronde S, Collins TJ, Shapovalova Z, Tanasijevic B, McNicol JD, Fiebig-Comyn A, Benoit YD, Lee JB, Mitchell RR, Bhatia M. Lee JH, et al. Among authors: mcnicol jd. Cell Rep. 2017 Apr 4;19(1):20-35. doi: 10.1016/j.celrep.2017.03.036. Cell Rep. 2017. PMID: 28380358 Free article.
Identification of cells of leukemic stem cell origin with non-canonical regenerative properties.
Hollands CG, Boyd AL, Zhao X, Reid JC, Henly C, ElRafie A, Boylan D, Broder E, Kalau O, Johnson P, Mark A, McNicol J, Xenocostas A, Berg T, Foley R, Trus M, Leber B, Garcia-Horton A, Campbell C, Bhatia M. Hollands CG, et al. Among authors: mcnicol j. Cell Rep Med. 2024 Apr 16;5(4):101485. doi: 10.1016/j.xcrm.2024.101485. Epub 2024 Apr 5. Cell Rep Med. 2024. PMID: 38582086 Free PMC article.
Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells.
Sachlos E, Risueño RM, Laronde S, Shapovalova Z, Lee JH, Russell J, Malig M, McNicol JD, Fiebig-Comyn A, Graham M, Levadoux-Martin M, Lee JB, Giacomelli AO, Hassell JA, Fischer-Russell D, Trus MR, Foley R, Leber B, Xenocostas A, Brown ED, Collins TJ, Bhatia M. Sachlos E, et al. Among authors: mcnicol jd. Cell. 2012 Jun 8;149(6):1284-97. doi: 10.1016/j.cell.2012.03.049. Epub 2012 May 24. Cell. 2012. PMID: 22632761 Free article.