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DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma.
Taffoni C, Marines J, Chamma H, Guha S, Saccas M, Bouzid A, Valadao AC, Maghe C, Jardine J, Park MK, Polak K, De Martino M, Vanpouille-Box C, Del Rio M, Gongora C, Gavard J, Bidère N, Song MS, Pineau D, Hugnot JP, Kissa K, Fontenille L, Blanchet FP, Vila IK, Laguette N. Taffoni C, et al. Among authors: jardine j. EMBO J. 2023 Apr 3;42(7):e111961. doi: 10.15252/embj.2022111961. Epub 2022 Dec 27. EMBO J. 2023. PMID: 36574362 Free PMC article.
CARD11 gain of function upregulates BCL2A1 expression and promotes resistance to targeted therapies combination in B-cell lymphoma.
Decombis S, Bellanger C, Le Bris Y, Madiot C, Jardine J, Santos JC, Boulet D, Dousset C, Menard A, Kervoelen C, Douillard E, Moreau P, Minvielle S, Moreau-Aubry A, Tessoulin B, Roue G, Bidère N, Le Gouill S, Pellat-Deceunynck C, Chiron D. Decombis S, et al. Among authors: jardine j. Blood. 2023 Nov 2;142(18):1543-1555. doi: 10.1182/blood.2023020211. Blood. 2023. PMID: 37562004
The PINK1 repertoire: Not just a one trick pony.
Pollock L, Jardine J, Urbé S, Clague MJ. Pollock L, et al. Among authors: jardine j. Bioessays. 2021 Nov;43(11):e2100168. doi: 10.1002/bies.202100168. Epub 2021 Oct 7. Bioessays. 2021. PMID: 34617288
New aspects of USP30 biology in the regulation of pexophagy.
Marcassa E, Kallinos A, Jardine J, Rusilowicz-Jones EV, Clague MJ, Urbé S. Marcassa E, et al. Among authors: jardine j. Autophagy. 2019 Sep;15(9):1634-1637. doi: 10.1080/15548627.2019.1615304. Epub 2019 Jun 9. Autophagy. 2019. PMID: 31356149 Free PMC article.
Dual role of USP30 in controlling basal pexophagy and mitophagy.
Marcassa E, Kallinos A, Jardine J, Rusilowicz-Jones EV, Martinez A, Kuehl S, Islinger M, Clague MJ, Urbé S. Marcassa E, et al. Among authors: jardine j. EMBO Rep. 2018 Jul;19(7):e45595. doi: 10.15252/embr.201745595. Epub 2018 Jun 12. EMBO Rep. 2018. PMID: 29895712 Free PMC article.
USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation.
Rusilowicz-Jones EV, Jardine J, Kallinos A, Pinto-Fernandez A, Guenther F, Giurrandino M, Barone FG, McCarron K, Burke CJ, Murad A, Martinez A, Marcassa E, Gersch M, Buckmelter AJ, Kayser-Bricker KJ, Lamoliatte F, Gajbhiye A, Davis S, Scott HC, Murphy E, England K, Mortiboys H, Komander D, Trost M, Kessler BM, Ioannidis S, Ahlijanian MK, Urbé S, Clague MJ. Rusilowicz-Jones EV, et al. Among authors: jardine j. Life Sci Alliance. 2020 Jul 7;3(8):e202000768. doi: 10.26508/lsa.202000768. Print 2020 Aug. Life Sci Alliance. 2020. PMID: 32636217 Free PMC article.