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Page 1
Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors.
He R, Wang J, Yu ZH, Moyers JS, Michael MD, Durham TB, Cramer JW, Qian Y, Lin A, Wu L, Noinaj N, Barrett DG, Zhang ZY. He R, et al. Among authors: qian y. J Med Chem. 2022 Oct 27;65(20):13892-13909. doi: 10.1021/acs.jmedchem.2c01143. Epub 2022 Oct 5. J Med Chem. 2022. PMID: 36197449 Free PMC article.
Structural Determinants of the γ-8 TARP Dependent AMPA Receptor Antagonist.
Lee MR, Gardinier KM, Gernert DL, Schober DA, Wright RA, Wang H, Qian Y, Witkin JM, Nisenbaum ES, Kato AS. Lee MR, et al. Among authors: qian y. ACS Chem Neurosci. 2017 Dec 20;8(12):2631-2647. doi: 10.1021/acschemneuro.7b00186. Epub 2017 Sep 5. ACS Chem Neurosci. 2017. PMID: 28825787
An anti-ANGPTL3/8 antibody decreases circulating triglycerides by binding to a LPL-inhibitory leucine zipper-like motif.
Balasubramaniam D, Schroeder O, Russell AM, Fitchett JR, Austin AK, Beyer TP, Chen YQ, Day JW, Ehsani M, Heng AR, Zhen EY, Davies J, Glaesner W, Jones BE, Siegel RW, Qian YW, Konrad RJ. Balasubramaniam D, et al. J Lipid Res. 2022 May;63(5):100198. doi: 10.1016/j.jlr.2022.100198. Epub 2022 Mar 17. J Lipid Res. 2022. PMID: 35307397 Free PMC article.
Crystal structure of the human PRMT5:MEP50 complex.
Antonysamy S, Bonday Z, Campbell RM, Doyle B, Druzina Z, Gheyi T, Han B, Jungheim LN, Qian Y, Rauch C, Russell M, Sauder JM, Wasserman SR, Weichert K, Willard FS, Zhang A, Emtage S. Antonysamy S, et al. Among authors: qian y. Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):17960-5. doi: 10.1073/pnas.1209814109. Epub 2012 Oct 15. Proc Natl Acad Sci U S A. 2012. PMID: 23071334 Free PMC article.
57 results