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Page 1
Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity.
Blood Adv. 2023 Sep 26;7(18):5382-5395. doi: 10.1182/bloodadvances.2023009967.
Blood Adv. 2023.
PMID: 37505194
Free PMC article.
Targeting GLUT1 in acute myeloid leukemia to overcome cytarabine resistance.
Åbacka H, Hansen JS, Huang P, Venskutonytė R, Hyrenius-Wittsten A, Poli G, Tuccinardi T, Granchi C, Minutolo F, Hagström-Andersson AK, Lindkvist-Petersson K.
Åbacka H, et al. Among authors: hagstrom andersson ak.
Haematologica. 2021 Apr 1;106(4):1163-1166. doi: 10.3324/haematol.2020.246843.
Haematologica. 2021.
PMID: 32554563
Free PMC article.
No abstract available.
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Duplex Sequencing Uncovers Recurrent Low-frequency Cancer-associated Mutations in Infant and Childhood KMT2A-rearranged Acute Leukemia.
Pilheden M, Ahlgren L, Hyrenius-Wittsten A, Gonzalez-Pena V, Sturesson H, Hansen Marquart HV, Lausen B, Castor A, Pronk CJ, Barbany G, Pokrovskaja Tamm K, Fogelstrand L, Lohi O, Norén-Nyström U, Asklin J, Chen Y, Song G, Walsh M, Ma J, Zhang J, Saal LH, Gawad C, Hagström-Andersson AK.
Pilheden M, et al. Among authors: hagstrom andersson ak.
Hemasphere. 2022 Sep 30;6(10):e785. doi: 10.1097/HS9.0000000000000785. eCollection 2022 Oct.
Hemasphere. 2022.
PMID: 36204688
Free PMC article.
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FLT3N676K drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis.
Hyrenius-Wittsten A, Pilheden M, Falqués-Costa A, Eriksson M, Sturesson H, Schneider P, Wander P, Garcia-Ruiz C, Liu J, Ågerstam H, Hultquist A, Lilljebjörn H, Stam RW, Järås M, Hagström-Andersson AK.
Hyrenius-Wittsten A, et al. Among authors: hagstrom andersson ak.
Leukemia. 2019 Sep;33(9):2310-2314. doi: 10.1038/s41375-019-0465-1. Epub 2019 Apr 5.
Leukemia. 2019.
PMID: 30953031
Free PMC article.
No abstract available.
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De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia.
Hyrenius-Wittsten A, Pilheden M, Sturesson H, Hansson J, Walsh MP, Song G, Kazi JU, Liu J, Ramakrishan R, Garcia-Ruiz C, Nance S, Gupta P, Zhang J, Rönnstrand L, Hultquist A, Downing JR, Lindkvist-Petersson K, Paulsson K, Järås M, Gruber TA, Ma J, Hagström-Andersson AK.
Hyrenius-Wittsten A, et al. Among authors: hagstrom andersson ak.
Nat Commun. 2018 May 2;9(1):1770. doi: 10.1038/s41467-018-04180-1.
Nat Commun. 2018.
PMID: 29720585
Free PMC article.
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SMS121, a new inhibitor of CD36, impairs fatty acid uptake and viability of acute myeloid leukemia.
Åbacka H, Masoni S, Poli G, Huang P, Gusso F, Granchi C, Minutolo F, Tuccinardi T, Hagström-Andersson AK, Lindkvist-Petersson K.
Åbacka H, et al. Among authors: hagstrom andersson ak.
Sci Rep. 2024 Apr 20;14(1):9104. doi: 10.1038/s41598-024-58689-1.
Sci Rep. 2024.
PMID: 38643249
Free PMC article.
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Sequential drug treatment targeting cell cycle and cell fate regulatory programs blocks non-genetic cancer evolution in acute lymphoblastic leukemia.
Malyukova A, Lahnalampi M, Falqués-Costa T, Pölönen P, Sipola M, Mehtonen J, Teppo S, Akopyan K, Viiliainen J, Lohi O, Hagström-Andersson AK, Heinäniemi M, Sangfelt O.
Malyukova A, et al. Among authors: hagstrom andersson ak.
Genome Biol. 2024 May 31;25(1):143. doi: 10.1186/s13059-024-03260-4.
Genome Biol. 2024.
PMID: 38822412
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