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Page 1
NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition.
Mol Cell. 2022 Jul 7;82(13):2472-2489.e8. doi: 10.1016/j.molcel.2022.04.015. Epub 2022 May 9.
Mol Cell. 2022.
PMID: 35537449
Free PMC article.
Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer.
Song L, Yao X, Li H, Peng B, Boka AP, Liu Y, Chen G, Liu Z, Mathias KM, Xia L, Li Q, Mir M, Li Y, Li H, Wan L.
Song L, et al. Among authors: mathias km.
Mol Cell. 2022 Nov 3;82(21):4080-4098.e12. doi: 10.1016/j.molcel.2022.09.034. Epub 2022 Oct 21.
Mol Cell. 2022.
PMID: 36272410
Free PMC article.
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Dysregulation of transcriptional condensates in human disease: mechanisms, biological functions, and open questions.
Mathias KM, Liu Y, Wan L.
Mathias KM, et al.
Curr Opin Genet Dev. 2024 May 23;86:102203. doi: 10.1016/j.gde.2024.102203. Online ahead of print.
Curr Opin Genet Dev. 2024.
PMID: 38788489
Review.
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Rhabdoid Tumors Are Sensitive to the Protein-Translation Inhibitor Homoharringtonine.
Howard TP, Oberlick EM, Rees MG, Arnoff TE, Pham MT, Brenan L, DoCarmo M, Hong AL, Kugener G, Chou HC, Drosos Y, Mathias KM, Ramos P, Seashore-Ludlow B, Giacomelli AO, Wang X, Freeman BB 3rd, Blankenship K, Hoffmann L, Tiv HL, Gokhale PC, Johannessen CM, Stewart EA, Schreiber SL, Hahn WC, Roberts CWM.
Howard TP, et al. Among authors: mathias km.
Clin Cancer Res. 2020 Sep 15;26(18):4995-5006. doi: 10.1158/1078-0432.CCR-19-2717. Epub 2020 Jul 6.
Clin Cancer Res. 2020.
PMID: 32631955
Free PMC article.
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Condensate-promoting ENL mutation drives tumorigenesis in vivo through dynamic regulation of histone modifications and gene expression.
Liu Y, Li Q, Song L, Gong C, Tang S, Budinich KA, Vanderbeck A, Mathias KM, Wertheim GB, Nguyen SC, Outen R, Joyce EF, Maillard I, Wan L.
Liu Y, et al. Among authors: mathias km.
Cancer Discov. 2024 Apr 24. doi: 10.1158/2159-8290.CD-23-0876. Online ahead of print.
Cancer Discov. 2024.
PMID: 38655899
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