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ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency.
Mol Cell. 2021 Sep 2;81(17):3604-3622.e10. doi: 10.1016/j.molcel.2021.07.018. Epub 2021 Aug 5.
Mol Cell. 2021.
PMID: 34358447
Free PMC article.
The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade.
Cucolo L, Chen Q, Qiu J, Yu Y, Klapholz M, Budinich KA, Zhang Z, Shao Y, Brodsky IE, Jordan MS, Gilliland DG, Zhang NR, Shi J, Minn AJ.
Cucolo L, et al. Among authors: budinich ka.
Immunity. 2022 Apr 12;55(4):671-685.e10. doi: 10.1016/j.immuni.2022.03.007.
Immunity. 2022.
PMID: 35417675
Free article.
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Genetic screening for single-cell variability modulators driving therapy resistance.
Torre EA, Arai E, Bayatpour S, Jiang CL, Beck LE, Emert BL, Shaffer SM, Mellis IA, Fane ME, Alicea GM, Budinich KA, Weeraratna AT, Shi J, Raj A.
Torre EA, et al. Among authors: budinich ka.
Nat Genet. 2021 Jan;53(1):76-85. doi: 10.1038/s41588-020-00749-z. Epub 2021 Jan 4.
Nat Genet. 2021.
PMID: 33398196
Free PMC article.
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High-performance CRISPR-Cas12a genome editing for combinatorial genetic screening.
Gier RA, Budinich KA, Evitt NH, Cao Z, Freilich ES, Chen Q, Qi J, Lan Y, Kohli RM, Shi J.
Gier RA, et al. Among authors: budinich ka.
Nat Commun. 2020 Jul 13;11(1):3455. doi: 10.1038/s41467-020-17209-1.
Nat Commun. 2020.
PMID: 32661245
Free PMC article.
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Condensate-promoting ENL mutation drives tumorigenesis in vivo through dynamic regulation of histone modifications and gene expression.
Liu Y, Li Q, Song L, Gong C, Tang S, Budinich KA, Vanderbeck A, Mathias KM, Wertheim GB, Nguyen SC, Outen R, Joyce EF, Maillard I, Wan L.
Liu Y, et al. Among authors: budinich ka.
Cancer Discov. 2024 Apr 24. doi: 10.1158/2159-8290.CD-23-0876. Online ahead of print.
Cancer Discov. 2024.
PMID: 38655899
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