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Page 1
Small-molecule inhibitors of human mitochondrial DNA transcription.
Nature. 2020 Dec;588(7839):712-716. doi: 10.1038/s41586-020-03048-z. Epub 2020 Dec 16.
Nature. 2020.
PMID: 33328633
Gasdermin D plays a vital role in the generation of neutrophil extracellular traps.
Sollberger G, Choidas A, Burn GL, Habenberger P, Di Lucrezia R, Kordes S, Menninger S, Eickhoff J, Nussbaumer P, Klebl B, Krüger R, Herzig A, Zychlinsky A.
Sollberger G, et al. Among authors: di lucrezia r.
Sci Immunol. 2018 Aug 24;3(26):eaar6689. doi: 10.1126/sciimmunol.aar6689.
Sci Immunol. 2018.
PMID: 30143555
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Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity.
Jiang S, Yuan T, Rosenberger FA, Mourier A, Dragano NRV, Kremer LS, Rubalcava-Gracia D, Hansen FM, Borg M, Mennuni M, Filograna R, Alsina D, Misic J, Koolmeister C, Papadea P, de Angelis MH, Ren L, Andersson O, Unger A, Bergbrede T, Di Lucrezia R, Wibom R, Zierath JR, Krook A, Giavalisco P, Mann M, Larsson NG.
Jiang S, et al. Among authors: di lucrezia r.
Nat Metab. 2024 Apr 30. doi: 10.1038/s42255-024-01038-3. Online ahead of print.
Nat Metab. 2024.
PMID: 38689023
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Potent agonists of the Hedgehog signaling pathway.
Brunton SA, Stibbard JH, Rubin LL, Guicherit OM, Kruse LI, Price S, di Lucrezia R, MacKinnon CH, Avery A, Park Y, Buxton D, Boyd EA.
Brunton SA, et al. Among authors: di lucrezia r.
Bioorg Med Chem Lett. 2009 Aug 1;19(15):4308-11. doi: 10.1016/j.bmcl.2009.05.096. Epub 2009 May 29.
Bioorg Med Chem Lett. 2009.
PMID: 19500978
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Psoromic acid is a selective and covalent Rab-prenylation inhibitor targeting autoinhibited RabGGTase.
Deraeve C, Guo Z, Bon RS, Blankenfeldt W, DiLucrezia R, Wolf A, Menninger S, Stigter EA, Wetzel S, Choidas A, Alexandrov K, Waldmann H, Goody RS, Wu YW.
Deraeve C, et al.
J Am Chem Soc. 2012 May 2;134(17):7384-91. doi: 10.1021/ja211305j. Epub 2012 Apr 22.
J Am Chem Soc. 2012.
PMID: 22480322
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