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Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase.
Brandon EP, Zhuo M, Huang YY, Qi M, Gerhold KA, Burton KA, Kandel ER, McKnight GS, Idzerda RL. Brandon EP, et al. Among authors: zhuo m. Proc Natl Acad Sci U S A. 1995 Sep 12;92(19):8851-5. doi: 10.1073/pnas.92.19.8851. Proc Natl Acad Sci U S A. 1995. PMID: 7568030 Free PMC article.
Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber pathways.
Huang YY, Bach ME, Lipp HP, Zhuo M, Wolfer DP, Hawkins RD, Schoonjans L, Kandel ER, Godfraind JM, Mulligan R, Collen D, Carmeliet P. Huang YY, et al. Among authors: zhuo m. Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8699-704. doi: 10.1073/pnas.93.16.8699. Proc Natl Acad Sci U S A. 1996. PMID: 8710934 Free PMC article.
Age-related defects in spatial memory are correlated with defects in the late phase of hippocampal long-term potentiation in vitro and are attenuated by drugs that enhance the cAMP signaling pathway.
Bach ME, Barad M, Son H, Zhuo M, Lu YF, Shih R, Mansuy I, Hawkins RD, Kandel ER. Bach ME, et al. Among authors: zhuo m. Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):5280-5. doi: 10.1073/pnas.96.9.5280. Proc Natl Acad Sci U S A. 1999. PMID: 10220457 Free PMC article.
761 results