Mullen CA - Search Results

1

Cytosine deaminase/5-fluorocytosine gene therapy can induce efficient anti-tumor effects and protective immunity in immunocompetent mice but not in athymic nude mice.

Kuriyama S, Kikukawa M, Masui K, Okuda H, Nakatani T, Sakamoto T, Yoshiji H, Fukui H, Ikenaka K, Mullen CA, Tsujii T. Kuriyama S, et al. Among authors: mullen ca. Int J Cancer. 1999 May 17;81(4):592-7. doi: 10.1002/(sici)1097-0215(19990517)81:4<592::aid-ijc15>3.0.co;2-i. Int J Cancer. 1999. PMID: 10225450 Free article.

2

Bystander effect caused by cytosine deaminase gene and 5-fluorocytosine in vitro is substantially mediated by generated 5-fluorouracil.

Kuriyama S, Masui K, Sakamoto T, Nakatani T, Kikukawa M, Tsujinoue H, Mitoro A, Yamazaki M, Yoshiji H, Fukui H, Ikenaka K, Mullen CA, Tsujii T. Kuriyama S, et al. Among authors: mullen ca. Anticancer Res. 1998 Sep-Oct;18(5A):3399-406. Anticancer Res. 1998. PMID: 9858915

3

Tumors expressing the cytosine deaminase suicide gene can be eliminated in vivo with 5-fluorocytosine and induce protective immunity to wild type tumor.

Mullen CA, Coale MM, Lowe R, Blaese RM. Mullen CA, et al. Cancer Res. 1994 Mar 15;54(6):1503-6. Cancer Res. 1994. PMID: 8137255

4

Radiosensitization by 5-fluorocytosine of human colorectal carcinoma cells in culture transduced with cytosine deaminase gene.

Khil MS, Kim JH, Mullen CA, Kim SH, Freytag SO. Khil MS, et al. Among authors: mullen ca. Clin Cancer Res. 1996 Jan;2(1):53-7. Clin Cancer Res. 1996. PMID: 9816090

5

Treatment of microscopic pulmonary metastases with recombinant autologous tumor vaccine expressing interleukin 6 and Escherichia coli cytosine deaminase suicide genes.

Mullen CA, Petropoulos D, Lowe RM. Mullen CA, et al. Cancer Res. 1996 Mar 15;56(6):1361-6. Cancer Res. 1996. PMID: 8640826

6

5-Fluorocytosine-induced eradication of murine adenocarcinomas engineered to express the cytosine deaminase suicide gene requires host immune competence and leaves an efficient memory.

Consalvo M, Mullen CA, Modesti A, Musiani P, Allione A, Cavallo F, Giovarelli M, Forni G. Consalvo M, et al. Among authors: mullen ca. J Immunol. 1995 May 15;154(10):5302-12. J Immunol. 1995. PMID: 7730633

7

Suicide gene therapy using E. coli beta-galactosidase.

Farquhar D, Pan BF, Sakurai M, Ghosh A, Mullen CA, Nelson JA. Farquhar D, et al. Among authors: mullen ca. Cancer Chemother Pharmacol. 2002 Jul;50(1):65-70. doi: 10.1007/s00280-002-0438-2. Epub 2002 Jun 8. Cancer Chemother Pharmacol. 2002. PMID: 12111114

8

Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system.

Mullen CA, Kilstrup M, Blaese RM. Mullen CA, et al. Proc Natl Acad Sci U S A. 1992 Jan 1;89(1):33-7. doi: 10.1073/pnas.89.1.33. Proc Natl Acad Sci U S A. 1992. PMID: 1729703 Free PMC article.

9

Bacterial infections in low-risk, febrile neutropenic patients.

Kamana M, Escalante C, Mullen CA, Frisbee-Hume S, Rolston KV. Kamana M, et al. Among authors: mullen ca. Cancer. 2005 Jul 15;104(2):422-6. doi: 10.1002/cncr.21144. Cancer. 2005. PMID: 15937905 Free article.

10

Gene therapy of cancer.

Mullen CA, Blaese RM. Mullen CA, et al. Cancer Chemother Biol Response Modif. 1996;16:285-94. Cancer Chemother Biol Response Modif. 1996. PMID: 8639387 Review. No abstract available.

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