Feng MR - Search Results

1

Synthesis of a series of 4-benzyloxyaniline analogues as neuronal N-type calcium channel blockers with improved anticonvulsant and analgesic properties.

Hu LY, Ryder TR, Rafferty MF, Feng MR, Lotarski SM, Rock DM, Sinz M, Stoehr SJ, Taylor CP, Weber ML, Bowersox SS, Miljanich GP, Millerman E, Wang YX, Szoke BG. Hu LY, et al. Among authors: feng mr. J Med Chem. 1999 Oct 7;42(20):4239-49. doi: 10.1021/jm9902739. J Med Chem. 1999. PMID: 10514294

2

The discovery of [1-(4-dimethylamino-benzyl)-piperidin-4-yl]-[4-(3,3-dimethylbutyl)-phen yl]-(3-methyl-but-2-enyl)-amine, an N-type Ca+2 channel blocker with oral activity for analgesia.

Hu LY, Ryder TR, Rafferty MF, Taylor CP, Feng MR, Kuo BS, Lotarski SM, Miljanich GP, Millerman E, Siebers KM, Szoke BG. Hu LY, et al. Among authors: feng mr. Bioorg Med Chem. 2000 Jun;8(6):1203-12. doi: 10.1016/s0968-0896(00)00077-8. Bioorg Med Chem. 2000. PMID: 10896101

3

Neuronal N-type calcium channel blockers: a series of 4-piperidinylaniline analogs with analgesic activity.

Hu LY, Ryder TR, Rafferty MF, Siebers KM, Malone T, Chatterjee A, Feng MR, Lotarski SM, Rock DM, Stoehr SJ, Taylor CP, Weber ML, Miljanich GP, Millerman E, Szoke BG. Hu LY, et al. Among authors: feng mr. Drug Des Discov. 2000;17(1):85-93. Drug Des Discov. 2000. PMID: 10928451

4

Mediation of highly concentrative uptake of pregabalin by L-type amino acid transport in Chinese hamster ovary and Caco-2 cells.

Su TZ, Feng MR, Weber ML. Su TZ, et al. Among authors: feng mr. J Pharmacol Exp Ther. 2005 Jun;313(3):1406-15. doi: 10.1124/jpet.104.082255. Epub 2005 Mar 15. J Pharmacol Exp Ther. 2005. PMID: 15769862

5

Identification, characterization and pharmacological profile of three metabolites of (R)-(+)-1,2,3,6-tetrahydro-4-phenyl-1-[(3-phenylcyclohexen-1- yl)methyl]pyridine (CI-1007), a dopamine autoreceptor agonist and potential antipsychotic agent.

Wright JL, Downing DM, Feng MR, Hayes RN, Heffner TG, MacKenzie RG, Meltzer LT, Pugsley TA, Wise LD. Wright JL, et al. Among authors: feng mr. J Med Chem. 1995 Dec 22;38(26):5007-14. doi: 10.1021/jm00026a007. J Med Chem. 1995. PMID: 8544176

6

Brain microdialysis and PK/PD correlation of pregabalin in rats.

Feng MR, Turluck D, Burleigh J, Lister R, Fan C, Middlebrook A, Taylor C, Su T. Feng MR, et al. Eur J Drug Metab Pharmacokinet. 2001 Jan-Jun;26(1-2):123-8. doi: 10.1007/BF03190385. Eur J Drug Metab Pharmacokinet. 2001. PMID: 11554426

7

Pharmacokinetics and pharmacodynamics of an investigational antipsychotic agent, CI-1007, in rats and monkeys.

Feng MR, Corbin AE, Wang Y, Christoffersen CL, Wiley JN, Strenkoski CA, Tucker EV, Ninteman FW, Meltzer LT, Heffner TG, Wright DS. Feng MR, et al. Pharm Res. 1997 Mar;14(3):329-36. doi: 10.1023/a:1012050121937. Pharm Res. 1997. PMID: 9098876

8

Sample pooling to expedite bioanalysis and pharmacokinetic research.

Kuo BS, Van Noord T, Feng MR, Wright DS. Kuo BS, et al. Among authors: feng mr. J Pharm Biomed Anal. 1998 Jan;16(5):837-46. doi: 10.1016/s0731-7085(97)00133-7. J Pharm Biomed Anal. 1998. PMID: 9535196

9

Disposition kinetics of cobalt mesoporphyrin in mouse, rat, monkey and dog.

Feng MR, Rossi DT, Strenkoski C, Black A, Dehart P, Lovdahl M, McNally W. Feng MR, et al. Xenobiotica. 1998 Apr;28(4):413-26. doi: 10.1080/004982598239515. Xenobiotica. 1998. PMID: 9604304

10

Allometric pharmacokinetic scaling: towards the prediction of human oral pharmacokinetics.

Feng MR, Lou X, Brown RR, Hutchaleelaha A. Feng MR, et al. Pharm Res. 2000 Apr;17(4):410-8. doi: 10.1023/a:1007520818956. Pharm Res. 2000. PMID: 10870984

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