Inhibition of nonsense-mediated decay rescues p53β/γ isoform expression and activates the p53 pathway in MDM2-overexpressing and select p53-mutant cancers.
Gudikote JP, Cascone T, Poteete A, Sitthideatphaiboon P, Wu Q, Morikawa N, Zhang F, Peng S, Tong P, Li L, Shen L, Nilsson M, Jones P, Sulman EP, Wang J, Bourdon JC, Johnson FM, Heymach JV.
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J Biol Chem. 2021 Nov;297(5):101163. doi: 10.1016/j.jbc.2021.101163. Epub 2021 Sep 3.
J Biol Chem. 2021.
PMID: 34481841
Free PMC article.