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Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation.
Freeman GJ, Long AJ, Iwai Y, Bourque K, Chernova T, Nishimura H, Fitz LJ, Malenkovich N, Okazaki T, Byrne MC, Horton HF, Fouser L, Carter L, Ling V, Bowman MR, Carreno BM, Collins M, Wood CR, Honjo T. Freeman GJ, et al. Among authors: bourque k. J Exp Med. 2000 Oct 2;192(7):1027-34. doi: 10.1084/jem.192.7.1027. J Exp Med. 2000. PMID: 11015443 Free PMC article.
PD-L2 is a second ligand for PD-1 and inhibits T cell activation.
Latchman Y, Wood CR, Chernova T, Chaudhary D, Borde M, Chernova I, Iwai Y, Long AJ, Brown JA, Nunes R, Greenfield EA, Bourque K, Boussiotis VA, Carter LL, Carreno BM, Malenkovich N, Nishimura H, Okazaki T, Honjo T, Sharpe AH, Freeman GJ. Latchman Y, et al. Among authors: bourque k. Nat Immunol. 2001 Mar;2(3):261-8. doi: 10.1038/85330. Nat Immunol. 2001. PMID: 11224527
IL-21 effects on human IgE production in response to IL-4 or IL-13.
Wood N, Bourque K, Donaldson DD, Collins M, Vercelli D, Goldman SJ, Kasaian MT. Wood N, et al. Among authors: bourque k. Cell Immunol. 2004 Sep-Oct;231(1-2):133-45. doi: 10.1016/j.cellimm.2005.01.001. Epub 2005 Feb 9. Cell Immunol. 2004. PMID: 15919378
Gβγ subunits colocalize with RNA polymerase II and regulate transcription in cardiac fibroblasts.
Khan SM, Martin RD, Bayne A, Pétrin D, Bourque K, Jones-Tabah J, Bouazza C, Blaney J, Lau J, Martins-Cannavino K, Gora S, Zhang A, MacKinnon S, Trieu P, Clarke PBS, Trempe JF, Tanny JC, Hébert TE. Khan SM, et al. Among authors: bourque k. J Biol Chem. 2023 Apr;299(4):103064. doi: 10.1016/j.jbc.2023.103064. Epub 2023 Feb 24. J Biol Chem. 2023. PMID: 36841480 Free PMC article.
36 results