Doan T - Search Results

1

Peripheral tolerance to human papillomavirus E7 oncoprotein occurs by cross-tolerization, is largely Th-2-independent, and is broken by dendritic cell immunization.

Doan T, Herd KA, Lambert PF, Fernando GJ, Street MD, Tindle RW. Doan T, et al. Cancer Res. 2000 Jun 1;60(11):2810-5. Cancer Res. 2000. PMID: 10850419

We previously have shown in mice transgenic for the E7 gene driven off an epithelial specific (keratin-14) promoter, that expression of E7 protein in peripheral epithelium is sufficient to tolerize E7-directed CTL precursors (pCTL; Doan et al, J. Virol., 73: 6166-1670, 199 …

We previously have shown in mice transgenic for the E7 gene driven off an epithelial specific (keratin-14) promoter, that expression of E7 p …

2

Limitations of HLA-transgenic mice in presentation of HLA-restricted cytotoxic T-cell epitopes from endogenously processed human papillomavirus type 16 E7 protein.

Street MD, Doan T, Herd KA, Tindle RW. Street MD, et al. Among authors: doan t. Immunology. 2002 Aug;106(4):526-36. doi: 10.1046/j.1365-2567.2002.01442.x. Immunology. 2002. PMID: 12153516 Free PMC article.

3

A polytope DNA vaccine elicits multiple effector and memory CTL responses and protects against human papillomavirus 16 E7-expressing tumour.

Doan T, Herd K, Ramshaw I, Thomson S, Tindle RW. Doan T, et al. Cancer Immunol Immunother. 2005 Feb;54(2):157-71. doi: 10.1007/s00262-004-0544-6. Epub 2004 Oct 7. Cancer Immunol Immunother. 2005. PMID: 15480657 Free PMC article.

4

Hepatitis B surface antigen vector delivers protective cytotoxic T-lymphocyte responses to disease-relevant foreign epitopes.

Woo WP, Doan T, Herd KA, Netter HJ, Tindle RW. Woo WP, et al. Among authors: doan t. J Virol. 2006 Apr;80(8):3975-84. doi: 10.1128/JVI.80.8.3975-3984.2006. J Virol. 2006. PMID: 16571814 Free PMC article.

5

Mice expressing the E7 oncogene of HPV16 in epithelium show central tolerance, and evidence of peripheral anergising tolerance, to E7-encoded cytotoxic T-lymphocyte epitopes.

Doan T, Chambers M, Street M, Fernando GJ, Herd K, Lambert P, Tindle R. Doan T, et al. Virology. 1998 May 10;244(2):352-64. doi: 10.1006/viro.1998.9128. Virology. 1998. PMID: 9601506 Free article.

6

Human papillomavirus type 16 E7 oncoprotein expressed in peripheral epithelium tolerizes E7-directed cytotoxic T-lymphocyte precursors restricted through human (and mouse) major histocompatibility complex class I alleles.

Doan T, Herd K, Street M, Bryson G, Fernando G, Lambert P, Tindle R. Doan T, et al. J Virol. 1999 Jul;73(7):6166-70. doi: 10.1128/JVI.73.7.6166-6170.1999. J Virol. 1999. PMID: 10364377 Free PMC article.

Mice which coexpress human papillomavirus type 16 E7 and HLA A2.1 in peripheral squamous epithelium and thymic cortical epithelium are tolerant at the cytotoxic T-lymphocyte (CTL) level to E7 epitopes restricted through HLA A*0201 and H-2(b) (T. Doan, M. Cham …

Mice which coexpress human papillomavirus type 16 E7 and HLA A2.1 in peripheral squamous epithelium and thymic cortical epithelium are toler …

7

Nonspecific down-regulation of CD8+ T-cell responses in mice expressing human papillomavirus type 16 E7 oncoprotein from the keratin-14 promoter.

Tindle RW, Herd K, Doan T, Bryson G, Leggatt GR, Lambert P, Frazer IH, Street M. Tindle RW, et al. Among authors: doan t. J Virol. 2001 Jul;75(13):5985-97. doi: 10.1128/JVI.75.13.5985-5997.2001. J Virol. 2001. PMID: 11390600 Free PMC article.

We have previously shown that E7-directed CTL down-regulation correlates with E7 expression in peripheral but not thymic epithelium (T. Doan et al., J. Virol. 73:6166-6170, 1999). The findings have implications for the immunological consequences of E7-expressing tum …

We have previously shown that E7-directed CTL down-regulation correlates with E7 expression in peripheral but not thymic epithelium (T …

8

Differences in the effectiveness of delivery of B- and CTL-epitopes incorporated into the hepatitis B core antigen (HBcAg) c/e1-region.

Street M, Herd K, Londono P, Doan T, Dougan G, Kast WM, Tindle RW. Street M, et al. Among authors: doan t. Arch Virol. 1999;144(7):1323-43. doi: 10.1007/s007050050590. Arch Virol. 1999. PMID: 10481740

9

Enhanced effector and memory CTL responses generated by incorporation of receptor activator of NF-kappa B (RANK)/RANK ligand costimulatory molecules into dendritic cell immunogens expressing a human tumor-specific antigen.

Wiethe C, Dittmar K, Doan T, Lindenmaier W, Tindle R. Wiethe C, et al. Among authors: doan t. J Immunol. 2003 Oct 15;171(8):4121-30. doi: 10.4049/jimmunol.171.8.4121. J Immunol. 2003. PMID: 14530334

10

Provision of 4-1BB ligand enhances effector and memory CTL responses generated by immunization with dendritic cells expressing a human tumor-associated antigen.

Wiethe C, Dittmar K, Doan T, Lindenmaier W, Tindle R. Wiethe C, et al. Among authors: doan t. J Immunol. 2003 Mar 15;170(6):2912-22. doi: 10.4049/jimmunol.170.6.2912. J Immunol. 2003. PMID: 12626542

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