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Page 1
Signal transduction by GABA(B) receptor heterodimers.
Jones KA, Tamm JA, Craig DA, Ph D, Yao W, Panico R. Jones KA, et al. Among authors: craig da. Neuropsychopharmacology. 2000 Oct;23(4 Suppl):S41-9. doi: 10.1016/S0893-133X(00)00145-7. Neuropsychopharmacology. 2000. PMID: 11008066 Review.
The novel neuropeptide Y Y5 receptor antagonist Lu AA33810 [N-[[trans-4-[(4,5-dihydro[1]benzothiepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl]-methanesulfonamide] exerts anxiolytic- and antidepressant-like effects in rat models of stress sensitivity.
Walker MW, Wolinsky TD, Jubian V, Chandrasena G, Zhong H, Huang X, Miller S, Hegde LG, Marsteller DA, Marzabadi MR, Papp M, Overstreet DH, Gerald CP, Craig DA. Walker MW, et al. Among authors: craig da. J Pharmacol Exp Ther. 2009 Mar;328(3):900-11. doi: 10.1124/jpet.108.144634. Epub 2008 Dec 19. J Pharmacol Exp Ther. 2009. PMID: 19098165
Synthesis and SAR investigations for novel melanin-concentrating hormone 1 receptor (MCH1) antagonists part 2: A hybrid strategy combining key fragments of HTS hits.
Chen CA, Jiang Y, Lu K, Daniewska I, Mazza CG, Negron L, Forray C, Parola T, Li B, Hegde LG, Wolinsky TD, Craig DA, Kong R, Wetzel JM, Andersen K, Marzabadi MR. Chen CA, et al. Among authors: craig da. J Med Chem. 2007 Aug 9;50(16):3883-90. doi: 10.1021/jm060383x. J Med Chem. 2007. PMID: 17668922
Anxiolytic- and antidepressant-like profiles of the galanin-3 receptor (Gal3) antagonists SNAP 37889 and SNAP 398299.
Swanson CJ, Blackburn TP, Zhang X, Zheng K, Xu ZQ, Hökfelt T, Wolinsky TD, Konkel MJ, Chen H, Zhong H, Walker MW, Craig DA, Gerald CP, Branchek TA. Swanson CJ, et al. Among authors: craig da. Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17489-94. doi: 10.1073/pnas.0508970102. Epub 2005 Nov 15. Proc Natl Acad Sci U S A. 2005. PMID: 16287967 Free PMC article.
Synthesis and SAR investigations for novel melanin-concentrating hormone 1 receptor (MCH1) antagonists Part 1. The discovery of arylacetamides as viable replacements for the dihydropyrimidinone moiety of an HTS hit.
Jiang Y, Chen CA, Lu K, Daniewska I, De Leon J, Kong R, Forray C, Li B, Hegde LG, Wolinsky TD, Craig DA, Wetzel JM, Andersen K, Marzabadi MR. Jiang Y, et al. Among authors: craig da. J Med Chem. 2007 Aug 9;50(16):3870-82. doi: 10.1021/jm060381c. J Med Chem. 2007. PMID: 17668921
50 results